Developmental Neuropathology

A definitive, clinically oriented guide to the pathology of genetics of developmental neuropathology Developmental neuropathology relates to the wide range of disorders affecting the developing brain or pre– and post–natal life, with emphasis on the genetic and molecular mechanisms involved. This book provides a practical guide to diagnosing and understanding these disorders affecting this vulnerable population and potentially stimulates further advances in this exciting area. It also addresses the controversies in inflicted head injury in infants. The fourth major title to be approved by the International Society of Neuropathology (ISN), Developmental Neuropathology offers in–depth chapter coverage of brain development; chromosomal changes; malformations; secondary malformations and destructive pathologies; developmental vascular disorders; acquired metabolic and exogenous toxins; metabolic disorders; Rett syndrome and autism; and infectious diseases. The text provides: Clinical, disease–oriented approach to the pathology and genetics developmental neuropathology Fuses classical and contemporary investigative approaches Includes genetic and molecular biological pathogeneses Fully illustrated Approved and endorsed by International Society of Neuropathology Developmental Neuropathology is the perfect book for practicing neuropathologists, pediatric pathologists, general pathologists, neurologists, and geneticists in deciphering the pathology and pathogenesis of these complex disorders affecting the nervous system of the embryo, fetus, and child. INDICE: List of contributors .Introduction .Chapter 1: CNS Manifestations of Chromosomal Change .Chapter 2: Neural tube defects .Chapter 3: MIDLINE  PATTERNING  DEFECTS .Chapter 4: MICROCEPHALY .Chapter 5: Hemimegalencephaly and Dysplastic Megalencephaly .Chapter 6: Lissencephaly, Type I .Chapter 7: Lissencephaly, Type II (Cobblestone Lissencephaly) .Chapter 8: Polymicrogyria .Chapter 9: Cerebral Heterotopia .Chapter 10: Hippocampal sclerosis and granule cell dysplasia, and cortical dysplasia .Chapter 11: Tuberous Sclerosis Complex .Chapter 12: Chiari Malformations .Chapter 13: Dandy–Walker Malformation, Mega–Cisterna Magna, and Blake?s Pouch Cyst .Chapter 14: Joubert Syndrome .Chapter 15: Cerebellar Heterotopia and Dysplasia .Chapter 16: Brainstem Malformations .Chapter 17: SPINAL CORD LESIONS .Chapter 18: HYDROCEPHALUS .Chapter 19: Antenatal Disruptive Lesions .Chapter 20: Hemorrhagic Lesions .Chapter 21: White Matter Lesions in the Perinatal Period .Chapter 22: Gray Matter Lesions .Chapter 23: Pediatric Head Injury .Chapter 24: Pediatric Vascular Malformations .Chapter 25: Sudden Infant Death Syndrome .Chapter 26: Kernicterus .Chapter 27: Lesions Induced by Toxins .Chapter 28: Disorders of Carbohydrate Metabolism .Chapter 29: Sphingolipidoses and related disorders  .Chapter 30: The Neuronal Ceroid–Lipofuscinoses .Chapter 31: Peroxisomal Disorders .Chapter 32: Mitochondrial Disorders .Chapter 33: DISORDERS OF AMINO ACID METABOLISM AND CANAVAN DISEASE .Chapter 34: Pelizaeus–Merzbacher Disease .Chapter 35: Cockayne Syndrome .Chapter 36: VANISHING WHITE MATTER DISEASE .Chapter 37: Alexander Disease .Chapter 38: Pathology and Genetics of Neuroaxonal Dystrophy/ Neurodegeneration with Brain Iron Accumulation .Chapter 39: Spinal Muscular Atrophy .Chapter 40: Autism Spectrum Disorders .Chapter 41: Intrauterine Infections .Chapter 42: Perinatal and Postnatal Infections .Chapter 43: Rasmussen Encephalitis

• ISBN: 978-1-119-01308-2
• Editorial: Wiley–Blackwell
• Encuadernacion: Cartoné
• Páginas: 560
• Fecha Publicación: 20/04/2018
• Nº Volúmenes: 1
• Idioma: Inglés