Pharmaceutical Biotechnology in Drug Development

Pharmaceutical Biotechnology in Drug Development summarizes the key concepts, and latest developments of biotechnology applied to the development of biopharmaceuticals.The book's content is organized in ten chapters. The first four chapters present a comprehensive collection of introductory biotechnology technologies and their modern concept, pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Chapters five and six explore therapeutic applications and the status of monoclonal antibodies, gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. The final group of chapters focus on emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand, such as utilization of transgenic plants and animals, metabolomics, plant-based biopharmaceuticals, identification of new and multiple biological targets, signaling pathways for membrane-spanning receptors, and lead discovery and modification.Pharmaceutical Biotechnology in Drug Development is an essential reference useful for pharmaceutical scientists, clinicians, and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book's succinct and objective content structure. Includes key concepts at the foundation of the technology relevant for protein therapeutics Explains how the advances in other areas such as genomics, proteomics and high-throughput screening have paved the way for exploring new avenues of drug discovery Covers the importance of biotechnology in the development of new biopharmaceuticals along with their pharmacodynamics and pharmacokinetics INDICE: 1. Introduction to modern concepts in pharmaceutical biotechnology and drug development2. Pharmacokinetic and pharmacodynamics of biotechnology products3. Role of biotechnology in amino acids modification4. Role of biotechnology in nucleic acid modification5. Monoclonal antibodies: Development, characterization and therapeutic application6. Development of nanoparticles: recent developments and future prospects7. Production of biopharmaceuticals from genetically modified organisms8. Metabolomics as bioanalytical approach for pharmaceutical biotechnology in drug development9. New biological targets for drug discovery and development10. Signaling pathways of membrane-spanning receptors for drug discovery and development

• ISBN: 978-0-443-19135-0
• Editorial: Academic Press
• Encuadernacion: Rústica
• Fecha Publicación: 01/06/2023
• Nº Volúmenes: 1
• Idioma: Inglés