Seldin and Giebischs The Kidney: Physiology and Pathophysiology

Seldin and Giebisch's The Kidney, Sixth Edition: Physiology and Pathophysiology provides a common language for nephrology researchers, fellows and practicing nephrologists to discuss normal and abnormal renal physiology and the development and diagnosis of a wide range of renal diseases. Guided by a team of four distinguished authorities in nephrology, experts from all areas of renal research and practice take readers from the structure and function of normal renal physiology, to the specific cellular and molecular mechanisms underlying disease development, and into the management of renal disease through physiologic regulation. This classic nephrology reference for nearly 30 years combines basic and clinical sciences that provides authoritative, concise and readily accessible information. Academic, medical and pharma researchers save valuable time by quickly accessing the very latest details on renal physiology and pathophysiology as opposed to searching through thousands of journal articles. Presents the most comprehensive, translational source for all aspects of normal renal physiology and pathophysiology of kidney diseases in one reference workOffers clear translational presentations by the top basic and clinical researchers in each specific renal disease, including transplantation, cancer, diabetic nephropathy, preeclampsia and glomerular diseaseIncludes a foreword by Drs. Donald Seldin and Gerhard Giebisch, both world- renowned names in nephrology and editors of previous editions INDICE: Volume 1 I: Epithelial and Nonepithelial Transport and Regulation 1. Epithelial Cell Structure and Polarity; 2. Mechanisms of Ion Transport across Cell Membranes; 3. Renal Ion-Translocating ATPases; 4. Mechanisms of Water Transport Across Cell Membranes and Epithelia; 5. Cell Volume Control; 6. Solute Transport, Energy Consumption, and Production in the Kidney; 7. Electrophysiological Analysis of Transepithelial Transport; 8. Renal Ion Channels, Electrophysiology of Transport, and Channelopathies; 9. Microvascular Permeability and the Exchange of Water and Solutes Across Microvascular Walls; 10. External Balance of Electrolytes and Acids and Alkali; 11. Renal Cilia Structure, Function, and Physiology; 12. Intercellular Junctions; 13. Principles of Cell Signaling; 14. Scaffolding Proteins in Transport Regulation; 15. The Renin-Angiotensin System; 16. Neural Control of Renal Function; 17. Eicosanoids and Renal Function; 18. Extracellular Nucleotides and Renal Function; 19. Paracrine Regulation of Renal Function by Dopamine II: Structural and Functional Organization of the Kidney 20. Structural Organization of the Mammalian Kidney; 21. Biophysical Basis of Glomerular Filtration; 22. Glomerular Cell Biology; 23. Function of the Juxtaglomerular Apparatus: Control of Glomerular Hemodynamics and Renin Secretion; 24. Renal Cortical and Medullary Microcirculations: Structure and Function; 25. Molecular and Cellular Mechanisms of Kidney Development; 26. Molecular and Cellular Mechanisms of Glomerular Capillary Development; 27. Postnatal Renal Development; 28. Renal Hyperplasia and Hypertrophy; 29. Stem Cells and Generation of New Cells in the Adult Kidney III: Fluid and Electrolyte Regulation and Dysregulation 30. Epithelial Na+ Channels; 31. Anion Channels; 32. Physiology and Pathophysiology of the NaCl Co-Transporters in the Kidney; 33. Sodium and Chloride Transport: Proximal Nephron; 34. Sodium Chloride Transport in the Loop of Henle, Distal Convoluted Tubule, and Collecting Duct; 35. Mineralocorticoid Action in the Aldosterone Sensitive Distal Nephron; 36. Inherited Disorders of Renal Salt Homeostasis: Insights from Molecular Genetics Studies; 37. Natriuretic Hormones; 38. Pathophysiology of Sodium Retention and Wastage; 39. Physiology and Pathophysiology of Hypertension; 40. Physiology and Pathophysiology of Diuretic Action; 41. Aquaporin Water Channels in Mammalian Kidney; 42. Thirst and Vasopressin; 43. The Urine Concentrating Mechanism and Urea Transporters; 44. Hyponatremia; 45. Hypernatremic States; 46. Polyuria and Diabetes Insipidus; 47. The Molecular Biology of Renal K+ Channels; 48. Extrarenal Potassium Metabolism; 49. Regulation of K+ Excretion; 50. Physiopathology of Potassium Deficiency Volume II 51. Clinical Disorders of Hyperkalemia; 52. Control of Intracellular pH; 53. SLC4 Sodium-Driven Bicarbonate Transporters; 54. The SLC4 Anion Exchanger Gene Family; 55. Cellular Mechanisms of Renal Tubular Acidification; 56. Chemoreceptors, Breathing and pH; 57. Renal Ammonium Ion Production and Excretion; 58. Clinical Syndromes of Metabolic Alkalosis; 59. Clinical Syndromes of Metabolic Acidosis; 60. Respiratory Acid-Base Disorders; 61. Mechanisms and Disorders of Magnesium Metabolism; 62. Calcium Channels; 63. The Calcium-Sensing Receptor; 64. Renal Calcium Metabolism; 65. The Hormonal Regulation of Calcium Metabolism; 66. Disorders of Calcium Metabolism; 67. Pathogenesis and Treatment of Nephrolithiasis; 68. Proximal Tubular Handling of Phosphate; 69. Clinical Disturbances of Phosphate Homeostasis; 70. Glucose Reabsorption in The Kidney; 71. Kidney Transport of Amino Acids and Oligopeptides, and Aminoacidurias; 72. Organic Anion and Cation Transporters in Renal Elimination of Drugs; 73. Renal Filtration, Transport, and Metabolism of Albumin and Albuminuria IV: Pathophysiology of Renal Disease 74. Physiologic Principles in the Clinical Evaluation of Electrolyte, Water, and Acid-Base Disorders; 75. Biomarkers for Assessment of Renal Function During Acute Kidney Injury; 76. Pathophysiology of Acute Kidney Injury; 77. Ischemic Renal Disease; 78. Pathophysiology and Pathogenesis of Diabetic Nephropathy; 79. Renal Failure in Cirrhosis; 80. Autosomal Dominant Polycystic Kidney Disease; 81. Renal Physiology and Disease in Pregnancy; 82. Immune and Inflammatory Glomerular Diseases; 83. Immunologic Mechanisms of Vasculitis; 84. Genetic Abnormalities in Glomerular Function; 85. Cellular Mechanisms of Drug Nephrotoxicity; 86. Role of Glomerular Mechanical Stress in the Pathogenesis of Chronic Kidney Disease; 87. Role of Proteinuria in the Progression of Renal Disease; 88. The Inflammatory Response to Ischemic Acute Renal Injury; 89. Catalytic (Labile) Iron in Kidney Disease; 90. Chronic Kidney Disease: Pathophysiology and the Influence of Dietary Protein; 91. Management of Calcium and Bone Disease in Renal Patients; 92. Hematopoiesis and the Kidney; 93. Individualizing the Dialysate to Address Electrolyte Disturbances in the Dialysis Patient; 94. Homeostasis of Solute and Water by the Transplanted Kidney; 95. Renal Disposition of Drugs and Translation to Dosing Strategies

• ISBN: 978-0-12-815389-5
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 3264
• Fecha Publicación: 01/09/2021
• Nº Volúmenes: 1
• Idioma: Inglés