Perinatal Stem Cells

Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton's jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. Explores current clinical and pre-clinical application of stem cells derived from perinatal sourcesOffers detailed insight into sources of perinatal stem cells and their potential for disease treatmentDiscusses progress in the manufacturing, banking and clinical translation of perinatal stem cellsEdited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells INDICE: Section I. Amniotic Fluid-Derived Stem Cells 1. In utero therapy for congenital disorders using amniotic fluid stem cells 2. The Amniotic Fluid Stem Cell Secretome: at the Heart of Regeneration 3. Transplantation of Amniotic Fluid-Derived Neural Stem Cells 4. Stroke therapy: the potential of amniotic fluid-derived stem cells 5. Vascular formation by human perinatal stem cells 6. Amniotic Fluid Stem Cells for Kidney Regeneration Section II. Placental and Placental Membrane-Derived Stem Cells 7. Placental mesenchymal stem cells for cellular cardiomyoplasty 8. Heterogeneous functions of perinatal mesenchymal stromal cells require a preselection before their banking for clinical use 9. Defining the fetal stem cell niche in the human placenta 10. Banking placental tissue hematopoietic stem cells and mesenchymal stem cells for clinical use 11. Immuno-modulatory mechanisms of placental stem cells 12. Amnion Membrane Allograft for Regenerative Medicine 13. Placental Stem Cells 14. Therapeutic Effect of Extracellular Vesicles Derived from Adult/Perinatal Human Mesenchymal Stem Cells Section III. Umbilical Cord-Derived Cells 15. Ex-vivo Expansion of Cord Blood Stem Cells 16. Cord Blood Transplantation: Therapeutic Use of Perinatal Stem Cells 17. Autologous Human Cord Blood as a Treatment for Traumatic Brain Injury in Children 18. Phenotypic and Functional Characterization Perinatal Stem Cells Isolated from Umbilical Cord Tissue 19. Mesenchymal stromal cells from Wharton's jelly (WJ-MSCs): coupling their hidden differentiative program with their frank immunomodulatory phenotype 20. Regeneration of ischemic cardiovascular damage using Jelly Wharton as an unlimited source of therapeutic stem cells 21. Phenotype with Focused Paracrine Fractions: Effecting Future Phenotype with Focused Paracrine Fractions Section IV. Clinical and Industry Perspective 22. Clinical Translation of Perinatal Stem Cell Therapy 23. Current Clinical Trials utilizing Perinatal Stem Cells - A Review 24. Review Of Processing Technology and Techniques for Perinatal Stem Cells Banking And Clinical Applications 25. Clinical Development And Commercialization Of Placenta-Derived Cell Therapy 26. How the patent landscape has changed 27. The Need for Better Assays to Predict the Effectiveness of Tissue Stem Cell Treatments

• ISBN: 978-0-12-812015-6
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 600
• Fecha Publicación: 01/06/2018
• Nº Volúmenes: 1
• Idioma: Inglés