Studies in Natural Products Chemistry, Volume 53, covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry that are discussed and highlighted in this series. Focuses on the chemistry of bioactive natural productsContains contributions by leading authorities in the fieldPresents sources of new pharmacophores INDICE: 1. Pharmacology and Structure-Activity Relationship of Natural Products with Psychoactive Effects from Salvia Divinorum, Mitragyna Speciosa, and Ayahuasca 2. Recent Developments on the Synthesis and Applications of Betulin and Betulinic Acid Derivatives as Therapeutic Agents 3. Synthetic Approaches To the Naturally Occuring Anticancer Amaryllidaceae Alkaloids Trans-Dihydrolycoricidine and Trans-Dihydronarciclasine 4. Total Synthesis of Schisandra Nortriterpenoids: History, Progress and Perspective 5. Chemical Synthesis of Meridianins and Related Derivatives 6. Biologically Active Isothiocyanates: Protecting Plants and Healthing Humans 7. Curcumin, a Multi-Target Phytochemical: Challenges and Perspectives 8. Bioactive Coumarins and Xanthones from Calophyllum Genus and Analysis of Their Drug Likeness and Toxicological Properties 9. Structure and Biological Functions of D-Glucans and Their Applications 10. Chemistry, Bioactivity and the Structure-Activity Relationship of Cephalotaxine-Type Alkaloids from Cephalotaxus Sp. 11. Analysis of the Protein Binding Sites for Thiamin and Its Derivatives to Elucidate Molecular Mechanisms of the Non-Coenzyme Action of Thiamin (Vitamin B1)
- ISBN: 978-0-444-63930-1
- Editorial: Elsevier
- Encuadernacion: Cartoné
- Páginas: 460
- Fecha Publicación: 01/05/2017
- Nº Volúmenes: 1
- Idioma: Inglés