Medicinal Chemistry for Organic Chemists provides the latest information on a topic that is one of the largest employers of chemists worldwide, with increasing numbers of universities around the world including the subject matter in their curricula. The book is designed to provide an entry-level introduction to the field of medicinal chemistry for advanced chemistry post-graduate and undergraduate students. Written from the perspective of organic chemists, and in the language of chemists, this book provides the basic information required to understand the field of drug discovery. It presents and addresses common misconceptions and misunderstandings through the inclusion of key points, and supports the readers' further development through the inclusion of numerous references that point out key sources of in-depth information in the original literature. Underpinning the theoretical background, numerous development examples of real life pharmaceutical targets from key drug classes are shown, illustrating in a practical, memorable way how real world drug discovery takes place. Written as a primer from the perspective of organic chemists in the language of chemistsProvides contextual and foundational information with plenty of references to the original literature and other in-depth textbooks and monographs for future studySupports theoretical knowledge with numerous examples from real-world cases to illustrate all points INDICE: Part 1: The Principles 1. Where do drugs come from and what are the roles of organic chemists in the drug discovery process? 2. Fundamentals of human biology 3. Pharmacology for chemists 4. How do we begin? Where drug leads come from. 5. Advancing leads to the clinic: Med chem tricks of the trade. Part 2: Drug Classes: Examples and Lessons 6. Orienteering through drug classes. 7. Neurology and Psychiatry 8. Homeostasis, hormone control, and inflammation 9. Infection 10. Cancer
- ISBN: 978-0-12-398533-0
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 448
- Fecha Publicación: 30/11/2016
- Nº Volúmenes: 1
- Idioma: Inglés