Bioinformatics and biomarker discovery: OMIC data analysis for personalized medicine

A research-level book, which will introduce biologists and cardiologists to fundamental data analysis principles, techniques and tools for supporting the discovery of biomarkers and diagnostic/prognostic prediction systems. The book can, however, also be used by computational biologists and bioinformaticians doing research in cardiovascular research. The focus will be on how fundamentalstatistical and data mining approaches can be used to support biomarker discovery and evaluation. It will emphasize applications using cardiovascular omic data and discuss design factors, requirements and techniques for disease screening, diagnostic and prognostic applications. The book will consist of foundation chapters, which will provide readers with the knowledge needed to assess the requirements, design factors and outputs of disease biomarker research. These will be followed by detailed discussions of methodologies and applications based on specific types of omic data, as well as their integration. Such chapters will reflect the how and what aspects of these research areas. Concluding chapters will focus on the critical assessment of current knowledge gaps, bioinformatic challenges and emerging research directions. This will underscore the why and when aspects of problems and applications.

• ISBN: 978-0-470-74460-4
• Editorial: John Wiley & Sons
• Encuadernacion: Cartoné
• Páginas: 230
• Fecha Publicación: 19/02/2010
• Nº Volúmenes: 1
• Idioma: Inglés