Holland-Frei Cancer Medicine

Holland–Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all–new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease  An emphasis on multidisciplinary, research–driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting–edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs INDICE: Part 1: INTRODUCTION .1 Cardinal manifestations of cancer 00 James F. Holland, Waun K. Hong,DonaldW. Kufe, Robert C. Bast,William N. Hait, Raphael E. Pollock, and Ralph R.Weichselbaum .2 Biological hallmarks of cancer 00 Douglas Hanahan and Robert A.Weinberg .Part 2: TUMOR BIOLOGY .3 Technologies and Models to Study Cancer 00 Srinivas R. Viswanathan,David A. Tuveson, and Matthew Meyerson .4 Oncogenes 00 Marco A. Pierotti, Milo Frattini, Francesca Molinari, Gabriella Sozzi, and Carlo M. Croce .5 Tumor suppressor genes 00 David Cosgrove, Ben H. Park, and Bert Vogelstein .6 Epigenetic contributions to human cancer 00 James G. Herman and Stephen B. Baylin .7 Cancer genomics and evolution 00 William P.D. Hendricks, Aleksandar Sekulic, Alan H. Bryce, Muhammed Murtaza, Pilar Ramos, and Jeffrey M. Trent .8 Chromosomal Abberations in Human Cancer 00 David VanderWeele, Megan E. McNerney, and Michelle M. Le Beau .9 MicroRNA expression in cancer 00 Serge Patrick Nana–Sinkam, Mario Acunzo, and Carlo M. Croce .10 Aberrant signaling pathways in cancer 00 Luca Grumolato and Stuart A. Aaronson .11 Differentiation therapy 00 Sai–Juan Chen, Xiao–Jing Yan, Guang–Biao Zhou, and Zhu Chen .12 Cancer stem cells 00 Yadwinder S. Deol, Jill Granger, and Max S.Wicha .13 Cancer Cell Death 00 John C. Reed .14 Cancer cell immortality: targeting telomerase 00 Ilgen Mender, Zeliha Gunnur Dikmen,Woodring E. Wright, and Jerry W. Shay .15 Cancer metabolism 00 Natalya N. Pavlova and Craig B.Thompson .16 Modeling therapy of late or early–stage metastatic disease in mice 00 Robert S. Kerbel, Marta Paez–Ribes, Shan Man, Ping Xu, Eric Guerin,William Cruz–Munoz, and John M. L. Ebos .17 Tumor angiogenesis 00 John V. Heymach, Amado Zurita–Saavedra, Scott Kopetz, Tina Cascone, and Monique Nilsson .Part 3: QUANTITATIVE ONCOLOGY .18 Cancer bioinformatics 00 John N.Weinstein .19 Systems biology and genomics 00 Saima Hassan, Laura M. Heiser, and JoeW. Gray .20 Statistical innovations in cancer research 00 J. Jack Lee and Donald A. Berry .21 Biomarker–based clinical trial design in the era of genomic medicine 00 Richard Simon and Martine J. Piccart–Gebhart .22 Clinical informatics 00 Edward P. Ambinder .Part 4: CARCINOGENESIS .23 Chemical carcinogenesis 00 Lorne J. Hofseth, AinsleyWeston, and Curtis C. Harris .24 Endocrine and genetic bases of hormone–related cancers 00 Leslie Bernstein, Xia Pu, and Jian Gu .25 Ionizing radiation 00 David J. Grdina .26 Ultraviolet radiation carcinogenesis 00 James E. Cleaver, Susana Ortiz–Urda, Radhika Gulhar, Sarah Arron, Lionel Brookes, andDavid L. Mitchell .27 Inflammation and cancer 00 Jelena Todoric, Atsushi Umemura, Koji Taniguchi, and Michael Karin .28 RNA tumor viruses 00 Robert C. Gallo and Marvin S. Reitz .29 Herpesviruses 00 Jeffrey I. Cohen .30 Papillomaviruses and cervical neoplasia 00 Michael F. Herfs, Martin C. Chang, and Christopher P. Crum .31 Hepatitis viruses and hepatoma 00 HongyangWang .32 Parasites 00 Mervat Z. El Azzouni, and Radwa G. Diab .Part 5: EPIDEMIOLOGY, PREVENTION AND DETECTION .33 The burden of cancer worldwide: current and future perspectives 00 Jacques Ferlay, Christopher P.Wild, and Freddie Bray .34 Cancer epidemiology 00 XifengWu, Xia Pu, Stephanie C. Melkonian, and Margaret R. Spitz .35 Behavioral approaches to cancer prevention 00 Errol J. Philip and Jamie S. Ostroff .36 Diet and nutrition in the etiology and prevention of cancer 00 Steven K. Clinton, Elizabeth M. Grainger, and Edward L. Giovannucci .37 Chemoprevention of cancer 00 William N.William,Waun K. Hong, and Scott M. Lippman .38 Cancer Screening and Early Detection 00 OtisW. Brawley .Part 6: CLINICAL DISCIPLINES .39 Nexgen Pathology: Predicting clinical course and targeting disease causation 00 Carlos Cordon–Cardo and Adolfo Firpo–Betancourt .40 Molecular diagnostics in cancer 00 Roshni D. Kalachand, Bryan T. Hennessy, Robert C. Bast, and Gordon B. Mills .41 Principles of Conventional and Molecular Imaging 00 Lawrence H. Schwartz .42 Interventional Radiology for the Cancer Patient 00 Judy Ahrar, Michael J.Wallace, and Rony Avritscher .43 Principles of Surgical Oncology 00 Mark Bloomston, Donald L. Morton , Raphael E. Pollock, Michael Choti, and Ken K. Tanabe .44 Principles of radiation oncology 00 Philip P. Connell and Ralph R.Weichselbaum .45 Principles of Medical Oncology 00 William N. Hait, James F. Holland, Emil Frei III, Donald W. Kufe, Robert C. Bast Jr., andWaun KiHong .46 Palliative care 00 Cardinale B. Smith .47 Principles of psycho–oncology 00 Jimmie C. Holland and TaliaW.Wiesel .48 Principles of cancer rehabilitation medicine 00 Michael D. Stubblefield, David C. Thomas, and Kristjan T. Ragnarsson .49 Integrative oncology in cancer care 00 Gabriel Lopez, Richard Lee, Alejandro Chaoul, M. Kay Garcia, and Lorenzo Cohen .50 Health services research 00 Michaela A. Dinan, Bradford R. Hirsch, and Amy Abernethy .Part 7: INDIVIDUALIZED TREATMENT .51 Personalized Medicine in Oncology Drug Development 00 William N. Hait .Part 8: CHEMOTHERAPY .52 Preclinical and early clinical development of chemotherapeutic drugs, mechanism–based agents and biologics 00 Axel–R. Hanauske and Daniel D. Von Hoff .53 Tumor growth kinetics 00 Elizabeth Comen, Theresa A. Gilewski, and Larry Norton .54 Principles of Dose, Schedule, and Combination Chemotherapy 00 William N. Hait and Joseph P. Eder .55 Pharmacology 00 Manish R. Sharma and Mark J. Ratain .56 Folate Antagonists 00 Peter Cole and Joseph R. Bertino .57 Pyrimidine and purine antimetabolites 00 Robert B. Diasio .58 Alkylating agents and platinum antitumor compounds 00 Zahid H. Siddik .59 DNA topoisomerase targeting drugs 00 AnishThomas, Susan Bates,William D. Figg Sr, and Yves Pommier .60 Microtubule–Targeting Natural Products 00 Eric Rowinsky .61 Endocrine therapy for hormone receptor positive breast cancer 00 Aman U. Buzdar, Shaheenah Dawood, Harold A. Harvey, and V. Craig Jordan .62 Drug resistance and its clinical circumvention 00 Jeffrey A.Moscow, KennethH. Cowan, and Branimir I. Sikic .Part 9: BIOLOGICAL AND GENE THERAPY .63 Cytokines, interferons, and hematopoietic growth factors 00 Suhendan Ekmekcioglu and Elizabeth A. Grimm .64 Monoclonal serotherapy 00 Robert C. Bast, Michael R. Zalutsky, and Arthur E. Frankel .65 Vaccines and immunostimulants 00 Jeff Schlom .66 Cell–based cancer immunotherapy 00 Krina K. Patel, Judy S. Moyes, and Laurence J. Cooper .67 Cancer immunotherapy 00 Padmanee Sharma, Sumit K. Subudhi, Karl Peggs, Sangeeta Goswami, Jianjun Gao, Sergio Quezada, and James P. Allison .68 Cancer gene therapy 00 Haruko Tashiro and Malcolm Brenner .69 Cancer nanotechnology 00 Yanlan Liu, Danny Liu, Jinjun Shi, and Robert S. Langer .70 Hematopoietic cell transplantation 00 Roy Jones, Elizabeth Shpall, and Richard Champlin .Part 10: SPECIAL POPULATIONS .71 Principles of pediatric oncology 00 Teena Bhatla andWilliam L. Carroll .72 Cancer and pregnancy 00 Jennifer K. Litton .73 Cancer and aging 00 ArtiHurria,Hyman B. Muss, and Harvey J. Cohen .74 Disparities in Cancer Care 00 Otis Brawley .75 Immunoeffeciently related cancers 00 David T. Scadden and Jeremy S. Abramson .76 Cancer survivorship: new challenge in cancer medicine 00 Julia H. Rowland .Part 11: DISEASE SITES .77 Primary and metastatic neoplasms of the brain in adults 00 Lisa M. DeAngelis .78 Neoplasms of the eye 00 Jasmine H. Francis, Amy C. Schefler, and David H. Abramson .79 Neoplasms of the endocrine glands 00 Chirag D. Ghandi, Margaret Pain, and Kalmon Post .80 Neoplasms of the thyroid 00 Steven I. Sherman, Maria E. Cabanillas, and Stephen Lai .81 Neoplasms of the Adrenal Cortex 00 Tito Fojo .82 Tumors of the diffuse neuroendocrine and gastroenteropancreatic system 00 Evan Vosburgh .83 Neoplasms of the head and neck 00 Renata Ferrarotto, Merrill S. Kies, Adam S. Garden, and Michael E. Kupferman .84 Cancer of the Lung 00 Charles Lu, Daniel Morgensztern, Anne Chiang, Amir Onn, Boris Sepesi, Ara A. Vaporciyan, Joe Y. Chang, Ritsuko Komaki, Ignacio I. Wistuba, and Roy S. Herbst .85 Malignant pleural mesothelioma 00 Daniel R. Gomez, Anne S. Tsao, Haining Yang, and Harvey I. Pass .86 Thymomas andThymic Tumors 00 Alberto Marchevsky and Ronan Kelly .87 Tumors of the heart and great vessels 00 Anthony F. Yu, Sai–Ching J. Yeung, Carmen P. Escalante, Sarina van der Zee, A. P. Chahinian, and Valentin Fuster .88 Primary germ cell tumors of the thorax 00 John D. Hainsworth and F. Anthony Greco .89 Neoplasms of the Esophagus 00 MaxW. Sung, Virginia R. Litle, Steven J. Chmura, Stephen G. Swisher, David C. Rice, Jaffer A. Ajani, Ritsuko K. Komaki, andMark K. Ferguson .90 Carcinoma of the Stomach 00 Carl Schmidt, Mariela Blum Murphy, James C. Yao, and Christopher Crane .91 Primary neoplasms of the liver 00 Junichi Shindoh, KristofferW. Brudvik, and Jean–Nicolas Vauthey .92 Gallbladder and Bile Duct Cancer 00 Ahmed O. Kaseb, Melanie B. Thomas, Steven A. Curley .93 Neoplasms of the Exocrine Pancreas 00 Robert A.Wolff, Christopher H. Crane, Donghui Li, Douglas B. Evans, AnirbanMaitra, and Susan Tsai .94 Neoplasms of the colon, small intestine, vermiform appendix and peritoneum 00 Doug Tyler and Georgia Beasley .95 Neoplasms of the anus 00 Bruce D. Minsky and Jose G. Guillem .96 Renal cell carcinoma 00 Earle F. Burgess, Stephen B. Riggs, Brian I. Rini, and Derek Raghavan .97 Urothelial Cancer 00 Derek Raghavan, Richard Cote, Earle F. Burgess, Stephen B. Riggs, and Michael Haake .98 Neoplasms of the Prostate 00 Christopher J. Logothetis, Jeri Kim, JohnW. Davis, Brian F. Chapin, Deborah Kuban, Eleni Efstathiou, and Ana Aparicio .99 Tumors of the penis and urethra 00 Raymond Lance and Michael B.Williams .100 Testis cancer 00 Craig Nichols, Lawrence Einhorn, and Christian Kollmannsberger .101 Cancer of the vulva and vagina 00 Jacob Rotmensch and Summer Dewdney .102 Neoplasms of the cervix 00 Anuja Jhingran .103 Endometrial cancer 00 Jamal Rahaman, Karen Lu, and Carmel J. Cohen .104 Epithelial ovarian, fallopian tube, and peritoneal cancer 00 Jonathan S. Berek, Michael L. Friedlander, Robert C. Bast Jr. .105 Nonepithelial Ovarian Malignancies 00 Jonathan S. Berek, Michael L. Friedlander, and Robert C. Bast .106 Molar pregnancy and gestational trophoblastic neoplasia 00 Donald P. Goldstein, Ross S. Berkowitz, and Neil S. Horowitz .107 Gynecologic sarcomas 00 Jamal Rahaman and Carmel J. Cohen .108 Neoplasms of the Breast 00 Hope Rugo .109 Malignant Melanoma 00 Kim Margolin, Vernon Sondak, Susan Swetter, Scott Woodman, Jonathan Zager and Justin Ko .110 Other skin cancers 00 William G. Stebbins, Eric A. Millican, and Victor A. Neel .111 Bone Tumors 00 Tim Damron .112 Soft Tissue Sarcomas 00 Robert G. Maki, Chandrajit P. Raut, and Brian OffkSullivan .113 The Myelodyplastic Syndrome 00 Lewis R. Silverman .114 Acute Myeloid Leukemia in Adults: Mast Cell Leukemia and Other Mast Cell Neoplasms 00 Charles A. Schiffer and Richard Stone .115 Chronic myeloid leukemia 00 Jorge Cortes, Richard T. Silver, and Hagop M. Kantarjian .116 Acute lymphoblastic leukemia 00 Nitin Jain, Stefan Faderl, Hagop Kantarjian, and Susan O Brien .117 Chronic Lymphocytic Leukemia and Hairy Cell Leukemia 00 Kanti R. Rai and Jacquie Barrientos .118 Hodgkin lymphoma 00 Carol S. Portlock, Anita Kumar, and James Armitage .119 Non–Hodgkin Lymphoma 00 Arnold S. Freedman and Ann S. LaCasce .120 Mycosis fungoides and Sèzary syndrome 00 Richard T. Hoppe, Youn H. Kim, and Ranjana H. Advani .121 Plasma Cell Tumors 00 Kenneth C. Anderson .122 Myeloproliferative Neoplasms: Essential Thrombocythemia, Primary Myelofibrosis and Polycythemia Vera 00 AyalewTefferi .123 Neoplasms of Unknown Primary Site 00 John D. Hainsworth and F. Anthony Greco .Part 12: MANAGEMENT OF CANCER COMPLICATIONS .124 Anorexia and cachexia 00 Takao Ohnuma .125 Antiemetic Therapy 00 Patrick M. Forde, David S. Ettinger .126 Neurologic complications of cancer 00 Lisa M. DeAngelis .127 Dermatologic Complications of Cancer Chemotherapy 00 Anisha B. Patel and Madeleine M. Duvic .128 Skeletal complications 00 Michael A. Via, Ilya Iofin, and Jeffrey I. Mechanick .129 Hematologic complications and blood bank support 00 Richard M. Kaufman and Kenneth C. Anderson .130 Coagulopathic complications of cancer patients 00 Maria T. De Sancho and Jacob H. Randa .131 Urologic complications 00 Rachel A. Sanford, Ala Abudayyeh, Christopher J. Logothetis, andNizar M. Tannir .132 Cardiac Complications 00 Michael S. Ewer .133 Respiratory Complications 00 Vickie R. Shannon, George A. Eapen, Carlos A. Jimenez, Rodolfo C. Morice, Elizabeth L. Travis, Lara Bashoura, Scott E. Evans, Roberto Adachi, Saadia A. Faiz, Diwakar .D. Balachandran, S. Egbert Pravinkumar, Burton F. Dickey, Horiana B. Grosu, andMichaelH. Kroll .134 Gastrointestinal and hepatic complications in cancer patients 00 Robert S. Bresalier, H. Franklin Herlong, and Boris Blechacz .135 Oral complications of cancer and their treatment 00 Stephen T. Sonis and Anna Yuan .136 Gonadal complications 00 Vignesh Narayanan and Catherine E. Klein .137 Sexual dysfunction 00 Leslie R. Schover .138 Endocrine complications and paraneoplastic syndromes 00 S. JimYeung and Robert F. Gagel .139 Infections in patients with cancer 00 Lior Nesher and Kenneth V.I. Rolston .140 Oncologic emergencies 00 Sai–Ching Jim Yeung and Carmen P. Escalante .Part 13: THE FUTURE OF ONCOLOGY .141 A vision for 21st century healthcare 00 Leroy Hood, Kristin Brogaard, and Nathan D. Price

• ISBN: 978-1-118-93469-2
• Editorial: Wiley–Blackwell
• Encuadernacion: Cartoné
• Páginas: 2040
• Fecha Publicación: 19/01/2017
• Nº Volúmenes: 1
• Idioma: Inglés