Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality. Provides information on the timely nature of the included topics, which represent the most current concepts and approaches in cancer research Offers outstanding and original reviews on colorectal cancer research Provides the authority and expertise of the authors, all of whom are highly recognized and conducting state-of-the-art investigations in cancer, with this release focusing on colorectal cancer INDICE: 1. Early age onset colorectal cancer Swati G. Patel, Caitlin C. Murphy, Christopher H. Lieu, and Heather Hampel2. Treatment-induced evolutionary dynamics in nonmetastatic locally advanced rectal adenocarcinomaSeth I. Felder, Jason B. Fleming, and Robert A. Gatenby2. Early colorectal cancer detection-Current and evolving challenges in evidence, guidelines, policy, and practicesRobert A. Smith, Stacey Fedewa, and Rebecca Siegel4. Personalized nutrition for colorectal cancerKai Wang and Mingyang Song5. Immunotherapy in colorectal cancerParul Agarwal, Dung T. Le, and Patrick M. Boland6. Racial and ethnic disparities in colorectal cancer incidence and mortalityJohn M. Carethers7. Genomic and epigenomic biomarkers in colorectal cancer: From diagnosis to therapyJuan Ruiz-Bañobre and Ajay Goel8. Field carcinogenesis for risk stratification of colorectal cancerDionne Rebello, Elliott Rebello, Matthew Custodio, Xixi Xu, Sanil Gandhi, and Hemant K. Roy9. Modeling colorectal cancers using multidimensional organoidsIbrahim M. Sayed, Amer Ali Abd El-Hafeez, Priti P. Maity, Soumita Das, and Pradipta Ghosh10. Unraveling the genomic landscape of colorectal cancer through mutational signaturesMarcos Díaz-Gay and Ludmil B. Alexandrov11. Epigenetic alterations in the gastrointestinal tract: Current and emerging use for biomarkers of cancerWilliam M. Grady
- ISBN: 978-0-12-824078-6
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 484
- Fecha Publicación: 18/06/2021
- Nº Volúmenes: 1
- Idioma: Inglés