Precision Medicine in Pediatric Health is an invaluable resource addressing the state-of-the-art tools, technologies, and social and ethical issues involved in fully realizing precision medicine in new pediatric research and healthcare.Disease risk assessment, genetic counseling, clinical sequencing, and pharmacogenomics have become increasingly important to researchers working to advance precision diagnostics and therapeutics for pediatric populations, and pediatricians pursuing improved health outcomes for their patients.This book adopts a holistic approach, grounded in key learning points and practical case studies of interest to interdisciplinary teams of researchers and clinicians working in pediatrics. Chapters contributed by field leaders first provide a thorough introduction to basic principles of precision medicine, its growing role in research and clinical care, and relevant technologies and digital health. From there, the book examines best practices and offers support for implementing precision medicine in new research and clinical settings, with chapters devoted to various specialties, including prenatal and fetal health, oncology, cardiology, neurology, rare disease, and developmental disorders. Precision therapeutics, including small molecule and gene and cell-based therapies, are also discussed, followed by a close look at ethical, legal, and social implications of precision medicine in pediatrics, patient perspectives, and next steps in research and clinical translation Provides succinct commentary and key learning points supporting the translation of precision and genomic medicine into new research and clinical practiceHighlights the practical use of precision medicine in the management of pediatric patients, relevant to various specialtiesA comprehensive volume written and edited by leading researchers and clinician-scientists INDICE: 1. Introduction to Precision Medicine SECTION 1: Technologies and Innovation 2. Sequencing technologies 3. Health technologies 4. Digital Health SECTION 2: Clinical care 5. Genetic counseling 6. Prenatal/Fetal Health 7. Precision Oncology 9. Orphan diseases 10. Cardiology 11. Pharmacogenomics 12. Clinical Care Coordination 13. Small molecule therapeutics 14. Gene and Cell based therapeutics SECTION 4: Ethical, legal and social implications 15. Ethical/Legal/Social aspect 16. Patient Perspective 17. The Future 18. Take home message/Conclusion
- ISBN: 978-0-12-817016-8
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 456
- Fecha Publicación: 01/03/2020
- Nº Volúmenes: 1
- Idioma: Inglés