Cancer Gene Therapy by Viral and Non-viral Vectors

INDICE: List of Contributors, vii Series Foreword, ix Preface, xi Part I Delivery Systems 1 Translational Cancer Research: Gene Therapy by Viral and Non–viral Vectors, 3 Vincenzo Cerullo, Kilian Guse, Markus Vähä–Koskela, and Akseli Hemminki 2 Retroviruses for Cancer Therapy, 21 Jiehua Zhou, Yue Ding, John C. Burnett, and John Rossi 3 DNA Plasmids for Non–viral Gene Therapy of Cancer, 39 Amer M. Najjar, Judy S.E. Moyes, and Laurence J.N. Cooper 4 Cancer Therapy with RNAi Delivered by Non–viral Membrane/Core Nanoparticles, 61 Andrew B. Satterlee and Leaf Huang Part II Targeted Expression 5 Cancer Gene Therapy by Tissue–specific and Cancer–targeting Promoters, 81 Jennifer L. Hsu, Longfei Huo, Chia–Wei Li, Yi–Hsin Hsu, Yan Wang, and Mien–Chie Hung 6 MicroRNAs as Drugs and Drug Targets in Cancer, 97 Hui Ling and George A. Calin Part III Principles of Clinical Trials in Gene Therapy 7 Regulatory Issues for Manufacturers of Viral Vectors and Vector–transduced Cells for Phase I/II Trials, 115 Adrian P. Gee and Zhuyong Mei 8 US Regulations Governing Clinical Trials in Gene Therapy, 131 Bambi Grilley 9 Remaining Obstacles to the Success of Cancer Gene Therapy, 151 Malcolm K. Brenner Index, 157

• ISBN: 978-1-118-50162-7
• Editorial: Wiley–Blackwell
• Encuadernacion: Cartoné
• Páginas: 176
• Fecha Publicación: 06/05/2014
• Nº Volúmenes: 1
• Idioma: Inglés