Protein chromatography: process development and scale-up

This guide is based on a training course that teaches the theoretical as wellas practical aspects of protein bioseparation to bioprocess professionals from academia and industry. It is divided into two large parts. The first part introduces chromatographic theory, including process design principles, to enable the reader to rationalize the set-up of a bioseparation process. The second part illustrates by way of case studies and sample protocols how the theory learned in the first part may be applied to real-life problems. Thus, the book provides all the necessary knowledge for effective process development in chromatographic bioseparation, both on small and large scale.Giorgio Carta received his PhD in Chemical Engineering from the University ofDelaware in 1984. Since then he has been a professor in the Department of Chemical Engineering at the University of Virginia, Charlottesville (USA), where his research focuses on transport phenomena and bioseparations. He regularly organizes professional courses on various aspects of bioseparations, including a course on protein chromatography development and scale-up together with Alois Jungbauer. Alois Jungbauer is the head of protein technology and downstream processing at the Department of Biotechnology of the University of Natural Resources and Applied Life Sciences in Vienna (Austria). For more than 20 years, Professor Jungbauer has worked in biochemical engineering, with a focus on biosparation, where he has published widely and holds 15 patents. For over 10 years, he has organized a biennial professional course in protein chromatography focused on mass transfer, dispersion, and scale-up.

• ISBN: 978-3-527-31819-3
• Editorial: Wiley-VCH
• Encuadernacion: Cartoné
• Páginas: 364
• Fecha Publicación: 14/04/2010
• Nº Volúmenes: 1
• Idioma: Inglés