This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis isplaced on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment.Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and their students or trainees. INDICE: Contributors Part I Introduction to Basic Neuroscience Section Editor: Eric J. Nestler Introduction: Eric J. Nestler 1. Overview of brain development John L.R. Rubenstein and Stewart A. Anderson 2. Neurochemical systems inthe central nervous system Ariel Y. Deutch and Robert H. Roth 3. Using basic electrophysiology to understand the neurobiology of mental illness Of Mental Illness Evelyn K. Lambe and George K. Aghajanian 4. Principles of signal transduction Jean-Antoine Girault and Paul Greengard 5. Mechanisms of neural plasticity Eric J. Nestler and Steven E. Hyman 6. Principles of molecular biology Steven E. Hyman and Eric J. Nestler 7. Functional genomics and models of mental illness Lisa M. Monteggia, William A. Carlezon Jr, and Ralph J. DiLeone 8. Epigenetics of psychiatric diseases Bryan E. McGill and Huda Y. Zoghbi Part II Methods of Clinical Neurobiological Research Section Editor: Carol A. Tamminga Introduction: Carol A. Tamminga 9. Contributions of epidemiology to the neurobiology of mental illness Kathleen R. Merikangas and Amanda Kalaydjian 10. Basic methods for clinical molecular genetics of psychiatric illness Joel Gelernter and Jaakko Lappalainen 11. Neurocognitive assessment for psychiatric disordersMichael F. Green, Junghee Lee, and Robert S. Kern 12. Cognitive neuroscience:Bridging thinking and feeling to the brain, and its implications for psychiatry Cameron S. Carter, John G. Kerns, and Jonathan D. Cohen 13. Neuroimaging methods using nuclear magnetic resonance Hanzhang Lu and Yihong Yang 14. Molecular brain imaging research in mental illness Jong-Hoon Kim, Diana Martinez, Mark Slifstein, and Anissa Abi-Dargham 15. Human postmortem brain research in mental illness syndromes Monica Beneyto, Etienne Sibille, and David A. Lewis 16. Neuroimmunology John M. Petitto, Dean G. Cruess, Martin J. Repetto, David R. Gettes, Tami Benton, and Dwight L. Evans 17. Drug discovery and development methods for mental illness Gary D. Tollefson Part III Psychoses Section Editor: Jeffrey Lieberman Introduction: Jeffrey Lieberman 18. Diagnosis of schizophrenia Michael B. First 19. Genetics of schizophrenia Xiangning Chen, Brien Riley and Kenneth S. Kendler 20. Neurobiological theories of schizophrenia David A. Lewis and David W. Volk 21. Postmortem and nn vivo structural pathology in schizophrenia Andrew J. Dwork, John F. Smiley, Tiziano Calibazzi, Matthew J. Hoptman 22. Cognitive neuroscience and neuroimaging in schizophrenia Aysenil Belgerand Deanna M. Barch 23. The neurochemistry of schizophrenia: A focus on dopamine and glutamate Anissa Abi-Dargham 24. Principles of pharmacotherapy of schizophrenia Carol A. Tamminga Part IV Mood Disorders Section Editor: Charles B. Nemeroff Introduction: Charles B. Nemeroff 25. Diagnostic classification of mood disorders: historical context and implications for neurobiology S. Nassir Ghaemi, and Frederick K. Goodwin 26. Genetics of mood disorders Falk W. Lohoff and Wade H. Berrettini 27. Animal models of mood disorders Inge Sillaber, Florian Holsboer, and Carsten T. Wotjak 28. Cellular plasticity cascades: Genes tobehavior pathways in the pathophysiology and treatment of bipolar disorder Lisa A. Catapano, Guang Chen, Jing Du, Carlos A. Zarate, Jr., and Husseini K. Manji 29. Neurochemical theories of depression: preclinial studies Ronald S. Duman 30. The neurochemistry of depressive disorders: Clinical studies Boadie Dunlop 31. Neuroimaging studies of mood disorders Wayne C. Drevets 32. Principlesof the pharmacology of depression Robert M. Berman, Jonathan Sporn, Joseph K.Belanoff, Dennis S. Charney, and Alan Schatzberg 33. Abnormalities of brain structure and function in mood disorders Victoria Arango and J. John Mann 34. Novel targets for antidepressant treatments Olivier Berton and Eric J. Nestler 35. The neurobiology of menstrual-cycle related mood disorders David R. Rubinow, Peter J. Schmidt, Samantha Meltzer-Brody, and Veronica Harsh 36. Depressionand medical illness Tami D. Benton, Paul Crits-Christoph, Benoit Dube, and Dwight L. Evans Part V Anxiety Disorders Section Editor: Antonia New Introduction: Antonia New 37. Diagnostic classification of anxiety disorders: DSM-V and beyond Murray B. Stein and O. Joseph Bienvenu 38. The molecular genetics of anxiety disorders Steven P. Hamilton and Abby J. Fyer 39. The neurobiology of fear and anxiety: Contributions of animal models to current understanding GregoryM. Sullivan, Jacek Debiec, David E. A. Bush, David M. Lyons, and Joseph E. LeDoux 40. Stress-induced structural and functional plasticity in the brain: protection, damage and brain-body communication Bruce S. McEwen 41. The neurobiology of anxiety disorders Amir Garakani, James W. Murrough, Dennis S. Charney, and Douglas Bremner 42. The neurobiology and treatment of obsessive compulsivedisorder Susan E. Swedo and Paul Grant 43. Neuroimaging studies of anxiety disorders Justine M. Kent and Scott L. Rauch 44. Pharmacotherapy of anxiety disorders Sanjay J. Mathew, Ellen J. Hoffman, and Dennis S. Charney 45. Animal models of addiction Eliot L. Gardner and Roy A. Wise Part VI Substance Abuse Disorders Section Editor: Steven E. Hyman Introduction: Steven E. Hyman 46. Cellular and molecular mechanisms of drug addiction Eric J. Nestler 47. Genetic epidemiology of substance use disorders Kathleen R. Merikangas and Kevin P. Conway48. Effects of drugs of abuse on brain development Barry M. Lester and Barry E. Kosofsky 49. PET and SPECT imaging in substance abuse research Joanna S. Fowler and Nora D. Volkow 50. Brain reward and fMRI P. Read Montague and Pearl H. Chiu 51. Principles of the pharmacotherapy of addictive disorders Charles P.O'Brien and Charles Dackis Part VII Dementia Section Editor: Mary Sano Introduction: Mary Sano 52. The genetics and pathogenesis of Alzheimer's disease andrelated dementias John Hardy 53. Diagnostic classifications: Relationship to the neurobiology of dementia Steven Daniel I. Kaufer and Steven T. DeKosky 54.Transgenic models of dementias Gregory A. Elder 55. Functional neuroanatomy of learning and memory Gary L. Wenk 56. Neurochemical systems involved in learning and memory Joanne Berger-Sweeney, Laura R. Schaevitz, and Karyn Frick 57. Neuropathological and neuroimaging studies of the hippocampus in normal aging and in Alzheimer's disease Effie M. Mitsis, Maciek Bobinski, Miroslaw Brys, Lidia Glodzik-Sobanska, Susan De Santi, Yi Li, Byeong-Che Kim, Lisa Mosconi, andMony J. De Leon 58. Abnormalities in brain structure on postmortem analysis of dementia Daniel P. Perl 59. Functional brain imaging studies in dementia Monte S. Buchsbaum, Adam Brickman, Jing Zhang, and Erin A. Hazlett 60. Principlesof pharmacotherapy of dementia Christine Bergmann and Mary Sano 61. Cognitiveimpairment in demyelinating disease Thomas M. Hyde 62. Dementia with lewy bodies David J. Burn, Elaine K. Perry, John T. O'Brien, Neil Archibald, ElizabetaB. Mukaetova-Ladinska, Joaquim Cerejeira, Daniel Collerton, Evelyn Jaros, Robert Perry, Margaret A. Piggott, Chris M. Morris, Andrew McLaren, Clive G. Ballard, and Ian G. McKeith 63. Dementia in Parkinson's disease Martin Goldstein and C. Warren Olanow 64. Mild cognitive impairment Brendan J. Kelley and RonaldC. Petersen 65. Frontotemporal dementia Steven Z. Chao, Indre Viskontas, and Bruce L. Miller 66. Vascular dementia Nancy Nielsen-Brown and Helena C. Chui Part VIII Psychiatric Disorders of Childhood Onset Section Editor: Daniel Pine Introduction: Daniel Pine 67. The neurobiology of intellectual disabilities Antonio Y. Hardan and Allan L. Reiss 68. Cognitive neuroscience approaches to typical and atypical development B.J. Casey and Sarah Durston 69. The neurobiology of impulsivity and self-regulatory control in children with attention-deficit/hyperactivity disorder Kerstin J. Plessen and Bradley S. Peterson 70. Childhood anxiety disorders: A cognitive neurobiological perspective Christopher S.Monk and Daniel S. Pine 71. Molecular genetics of childhood and adolescent onset psychiatric disorders Jeremy Veenstra-VanderWeele, Randy D. Blakely, and Edwin H. Cook, Jr. 72. Pediatric bipolar disorder Ellen Leibenluft 73. Neurobiology of child and adolescent depression Joan Kaufman, Andrs Martin, and HilaryBlumberg 74. Structural magnetic resonance imaging of typical pediatric braindevelopment Jay N. Giedd, Samantha White, and Mark Celano 75. Tourette's syndrome and tic realted disorders in children Paul J. Lombroso, Michael H. Block,and James F. Leckman 76. The neurobiology of childhood psychotic disorders Nitin Gogtay and Judith Rapoport 77. Developmental perspectives on psychopathology Mike Rutter 78. Neurobiology of autism and the pervasive developmental disorders Sarah Spence, Paul Grant, Audrey Thurm, and Susan Swedo Part IX Special Topic Areas Section Editor: Antonia New 79. Neuropsychiatry: The border between neurology and psychiatry William M. McDonald and Michael S. Okun 80. The neurobiology of personality disorders Antonia S. New, Joseph Triebwasser and Marianne Goodman 81. The neurobiology of aggression R. J. R. Blair 82. Sexual dysfunction and pharmacological treatment: Biological interactions Stuart N. Seidman, Steven P. Roose, Raymond C. Rosen 83. The neurobiology of social attachment Thomas R. Insel and James T. Winslow 84. The neurobiology of eating disorders Walter Kaye, Michael Strober, and David Jimerson 85. The neurobiology of sleep Giulio Tononi and Chiara Cirelli 86. The neurobiology of resilience Margaret Haglund, Paul Nestadt, Nicole S. Cooper, Steven Southwick, and Dennis S. Charney 87. A Brief History of Neural Evolution Daniel R. Wilson
- ISBN: 978-0-19-979826-1
- Editorial: Oxford University
- Encuadernacion: Rústica
- Páginas: 1504
- Fecha Publicación: 21/07/2011
- Nº Volúmenes: 1
- Idioma: Inglés