Organotransition Metals in Organic Synthesis: Fundamentals and Applications

Organotransition Metals in Organic Synthesis: Fundamentals and Applications

Chatterjee, Sugata

182,00 €(IVA inc.)

Organotransition Metals in Organic Synthesis: Fundamentals and Applications provides a fundamental understanding of how to use transition and main group metals to synthesize simple and complex molecules, with a high degree of selectivity. This book details the basic concepts, elementary reactions, latest developments of organometallic chemistry of the transition metals. Topics covered include electronic configuration and structural, methods for carbon-transition metal bond creation, cleavage of metal-carbon bonds to form new carbon-carbon bonds, chemo-, region-, stereo- and enantio- control, as well as heterogeneous organometallic reactions. Organotransition Metals in Organic Synthesis: Fundamentals and Applications is an ideal resource for researchers and students working with metals in organic synthesis and organometallic chemistry, including those having no prior exposure to organometallic chemistry in synthesis. Includes extensive coverage of methods for creating carbon-transition metal bonds, such as oxidative addition, oxidative coupling, hydro and carbometallation, carbonyl insertion, transmetallation and metal carbenes and metathesisIdeal for students and researchers new to the pharmaceutical industry or organometallic chemistry in general, covering foundational information as well as select advanced applicationsCovers metals in organic synthesis, unprecedented selectivity, clean reactions, mild conditions, high yields, as well as improvisation methods for existing synthesis methods INDICE: 1. Introduction2. Electronic Configuration and Structural formalism (18e rule)3. Methods to make carbon-transition metal bond3a. Oxidative addition3b. Oxidative coupling3c. Hydro and carbometallation3d. Carbonyl insertion3e. Transmetallation3f. Metal carbenes and metathesis4. Cleavage of metal-carbon bonds to form new carbon-carbon bond in a highly selective fashion5. Chemo, regio, stereo and enantio control6. Heterogeneous organometallic reaction7. Selected applications

  • ISBN: 978-0-12-818477-6
  • Editorial: Elsevier
  • Encuadernacion: Rústica
  • Páginas: 315
  • Fecha Publicación: 01/12/2020
  • Nº Volúmenes: 1
  • Idioma: Inglés