Macromolecular crystallization and crystal perfection

Structural biology is key to our understanding of the mechanisms of biological processes. This book describes current methods and future frontiers in crystal growth and use of X-ray and Neutron crystallography, in the context of the very successful current automation of crystallization and generation of synchrotron X-ray and neutron beams. INDICE: I: INTRODUCTION AND OVERVIEW; 1: Introduction; II: CRYSTALLIZATION; 2: Crystallization Theory; 3: Practical Methods of Crystallization; 4: Screening; 5: Optimization; 6: Strategies when high quality crystals cannot be obtained; 7: Membrane Proteins; 8: Alternative Approaches; III: DIFFRACTION; 9:Experimental Aspects; 10: Analysis of the Molecular Short-Range Order; 11: Analysis of the Long-Range Order; 12: Macromolecular Crystals and Twinning; 13: Other Macromolecular Crystal Diffraction Disorders; 14: Degradation and Improvement of Crystal Perfection; 15: Unusual Diffraction Geometries; 16: Making the Most of Difficult Crystals; 17: Protein Powders; 18: Complementary Techniques; IV: THE FUTURE; 19: The X-ray Laser and the Single Molecule; 20: Overall Summary and Future Thoughts; Glossary of Abbreviations, Terms, and Symbols; References; Index

• ISBN: 978-0-19-921325-2
• Editorial: Oxford University
• Encuadernacion: Cartoné
• Páginas: 240
• Fecha Publicación: 25/03/2010
• Nº Volúmenes: 1
• Idioma: Inglés