Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics

Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoringFocuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoringExplores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interferenceExplains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window INDICE: Overview of Therapeutic Drug Monitoring Immunoassays and Issues with Interference in Therapeutic Drug Monitoring Application of Chromatography Combined with Mass Spectrometry in Therapeutic Drug Monitoring Clinical Utility of Free Drug Monitoring Therapeutic Drug Monitoring of Newer Antiepileptic Drugs Therapeutic Drug Monitoring of Antiretrovirals Therapeutic Drug Monitoring in Infants and Children Therapeutic Drug Monitoring in Pregnancy Therapeutic Drug Monitoring in the Elderly Therapeutic Drug Monitoring in Obese Patients Special Issues in Therapeutic Drug Monitoring in Patients with Uremia, Liver Disease, and Critically Ill Patients Integrating Therapuetic Drug Monitoring and Pharmacogenomics Warfarin Pharmacogenomics Drug Monitoring in Alternative Matrices Integrating and Supporting Therapeutic Drug Monitoring in a Hospital System

• ISBN: 978-0-12-802025-8
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 376
• Fecha Publicación: 01/06/2016
• Nº Volúmenes: 1
• Idioma: Inglés