The Human Gonadotropins is a must-have reference for basic science researchers looking to maximize their knowledge in this specific field of study. Luteinizing hormone, follicle-stimulating hormone, and human chorionic gonadotropin are essential for reproduction and outlined in detail in this work, covering topics ranging from antibodies and immunoassays, to commercial products and standards, genetics, and receptors and intermediaries for gonadotropins. Dr. Laurence Cole has been recognized for his outstanding research throughout his illustrious career. He has received awards from the Institute for Anticancer Research, Biannual Prize for best research; American Association for Clinical Chemistry, Most Outstanding Research Contributor to Clinical Chemistry Prize; Gynecology Oncology, Outstanding Speaker Award; and International Society for Study of Trophoblastic Disease, Gold Medal for most outstanding research. This detailed resource pulls the recent research together in one volume, with one consistent voice. He has pulled all the intriguing research together in one volume. Covers the evolution, structure, synthesis, and functions of gonadotropins in meticulous detailIncludes sections on Degradation, Antibodies and Immunoassays, Commercial Products and Standards, and Receptors and IntermediariesDetails a section on Reproduction and Cancer, covering gestational trophoblastic diseases, ovarian cystic disorders, and hCG and cancer INDICE: A. Evolution 1. Evolution of Aa, GAH, FSH and LH 2. Evolution of CG and Development of Humans B. Structure of the Gonadotropins 3. Structure FSH Peptide/arbohydrate/3D Construction 4. Structure LH Peptide/Carbohydrate/3D Construction 5. Structure hCG Peptide/Carbohydrate/3D Construction 6. Multiple forms of hCG Peptide/Carbohydrate/3D Construction C. Synthesis of the Gonadotropins 7. Synthesis of the Gonadotropins D. Functions of the Gonadotropins 8. Functions of Gonadotropin Releasing Hormone and Inhibin 9. Function of FSH 10. Function of LH 11. Function of Hormone hCG 12. Function of Hyperglycosylated hCG and Extravillous Cytotrophoblast hCG E. Degradation of the Gonadotropins 13. Degradation hCG F. Antibodies and Immunoassays for the Gonadotropins 14. Antibodies and Immunoassays for hCG G. Commercial products and standards for Gonadotropins 15. Commercial Products and Standards for FSH 16. Commercial Products and Standards for LH 17. Commercial Products and Standards for hCG H. The Genetics of Gonadotropins 18. The genetics of FSH 19. The genetics of hCG and LH I. Sex Steroid Hormones 20. Estrogens and Progestogens 21. Male Steroidogenesis J. Female Reproduction 22. Female reproduction: Follicle Formation and Follicle Selection. 23. Female reproduction: Ovulation and Luteinization. 24. Fertilization and Blastocyst Formation 25. Illicit use of hCG in Dietary Programs and to Promote Anabolism K. Male Reproduction 26. Male Reproduction: sperm formation 27. Sperm Activation L. Adrenarche and Menarche 28. Adrenarche and Menarche in Girls 29. Adrenarche and Puberty in Boys M. Menstrual Cycle hCG 30. Pituitary Sulfated hCG 31. Hyperglycosylated hCG and Extravillous Cytotrophoblast hCG N. Pregnancy 32. hCG and Pregnancy Tests 33. False-positive hCG Pregnancy Tests 34. hCG and Pregnancy 35. Implantation and Pregnancy Failure 36. Deep Implantation, hCG and Gestational Hypertension, Preeclampsi O. Roles of Gonadotropins in Reproduction and Cancer 37. hCG and Gestational Trophoblastic Diseases 38. The Human Brain: Sexuality 39. Ovarian Cystic Disorders 40. hCG and Choriocarcinoma 41. hCG and Cancer P. Receptors and intermediaries for Gonadotropins 42. Hyperglycosylated hCG, Extravillous Cytotrophoblast hCG and TGFß Receptor 2 43. Receptor and Intermediators for FSH 44. Receptor and Intermediaries for LH and the Hormone hCG
- ISBN: 978-0-12-821676-7
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 400
- Fecha Publicación: 01/07/2020
- Nº Volúmenes: 1
- Idioma: Inglés