Molecular Pathology: The Molecular Basis of Human Disease

Molecular Pathology: The Molecular Basis of Human Disease, Second Edition has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular and cell biology. This comprehensive textbook serves as a multi-use resource that is appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students and advanced undergraduates. In addition, it is ideal for pathology residents and other postdoctoral fellows who want to advance their understanding of the molecular mechanisms of disease. As the molecular basis of human disease becomes better characterized and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, this book stands out as the most comprehensive textbook available. It is uniquely concerned with the molecular basis of major human diseases and disease processes. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the diseaseExplains the practice of molecular medicine? and the translational aspects of molecular pathologyTeaches from the perspective of integrative systems biology? Includes an ancillary website that hosts a complete set of PowerPoint slides, including images from the book, additional images and self-assessment questions INDICE: PART I: Essential Pathology - Mechanisms of Disease 1. Molecular Mechanisms of Cell Death 2. Acute and Chronic Inflammation 3. Infection and Host Response 4. Neoplasia PART II: Concepts in Molecular Biology and Genetics 5. Basic Concepts in Human Molecular Genetics 6. The Human Genome: Implications for the Understanding of Human Disease 7. The Human Transcriptome: Implications for the Understanding of Human Disease 8. The Human Epigenome: Implications for the Understanding of Human Disease 9. The Human Proteome: Implications for the Understanding of Human Disease 10. Integrative Systems Biology: Implications for the Understanding of Human Disease PART III: Principles and Practice of Molecular Pathology 11. Pathology: The Clinical Description of Human Disease 12. Molecular Pathogenesis: The Biological Basis of Human Disease 13. Integration of Molecular and Cellular Pathogenesis PART IV: Molecular Pathology of Human Disease 14. Molecular Basis of Cardiovascular Disease 15. Molecular Basis of Hemostatic and Thrombotic Diseases 16. Molecular Basis of Lymphoid and Myeloid Diseases 17. Molecular Basis of Diseases of Immunity 18. Molecular Basis of Pulmonary Disease 19. Molecular Basis of Diseases of the Gastrointestinal Tract 20. Molecular Basis of Liver Disease 21. Molecular Basis of Diseases of the Exocrine Pancreas 22. Molecular Basis of Diseases of the Endocrine System 23. Molecular Basis of Gynecologic Diseases 24. Molecular Basis of Prostate Disease 25. Molecular Basis of Breast Disease 26. Molecular Basis of Skin Disease 27. Molecular Basis of Diseases of the Nervous System PART V: Practice of Molecular Medicine  28. Molecular Diagnosis of Human Disease 29. Molecular Assessment of Human Disease in the Clinical Laboratory 30. Pharmacogenomics and Personalized Medicine in the Treatment of Human Disease

• ISBN: 978-0-12-802761-5
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 656
• Fecha Publicación: 01/10/2017
• Nº Volúmenes: 1
• Idioma: Inglés