Updated with new and expanded chapters, Endocrine Disruption and Human Health, Second Edition provides an introduction to what endocrine disruptors are, the issues surrounding them, the source of these chemicals in the ecosystem and the mechanisms of action and assay systems. Contributions by specialists are included to discuss the varying effects of endocrine disruption on human health, and procedures for risk assessment of endocrine disruptors, and current approaches to their regulation are also covered. With new material on topics such as low-term, low dose mixtures, windows of susceptibility, epigenetics, EDCs effect on the gut microbiome, EDCs in from polluted air and oral exposures, green chemistry, and nanotechnology, the new edition of Endocrine Disruption and Human Health is a valuable and informative text for academic and clinical researchers and other health professionals approaching endocrine disruption and its effects on human health for the first time, graduate students, and advanced undergraduate students. Provides readers with access to a range of information from the basic mechanisms and assays through to cutting-edge research investigating concerns for human health Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations Newly added content on topics like low-term, low dose mixtures, windows of susceptibility to EDCs, EDCs effect on the gut microbiome, green chemistry, and nanotechnology INDICE: SECTION 1 OVERVIEW and SCOPE 1. What is endocrine disruption? 2. Which chemicals are endocrine disruptors? SECTION 2 MECHANISMS and ASSAY SYSTEMS 3. Environmental oestrogens: Disrupters of oestrogen action 4. Disrupters of androgen action 5. Assay systems for studying endocrine disruption 6. Non-monotonic responses in endocrine disruption 7. Endocrine disrupters as modifiers of endogenous hormone synthesis SECTION 3 CONCERNS FOR HUMAN HEALTH 8. Endocrine disruption and female reproductive health 9. Endocrine disruption and breast cancer 10. Endocrine disruption and male reproductive health 11. Endocrine disruption and prostate cancer 12. Endocrine disruption and thyroid disease 13. Endocrine disruption of adrenal function 14. Endocrine disruption of developmental pathways and children's health 15. Endocrine disruption of immune function 16. Endocrine disruption and obesity, metabolic syndrome and type 2 diabetes 17. Endocrine disruption and cardiovascular disease 18. Transgenerational effects of endocrine disruption 19. Regulatory considerations
- ISBN: 978-0-12-821985-0
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 538
- Fecha Publicación: 23/09/2021
- Nº Volúmenes: 1
- Idioma: Inglés