Chimerism

This text provides a comprehensive, state-of-the-art review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focuses on the relationship between testing and forensics, prenatal genetic testing and screening, and blood typing discrepancies. This part also reviews new data concerning matching chimeric donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease, passenger lymphocyte syndrome, and autoimmune disease.  

Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts.