Wireless Computing in Medicine: From Nano to Cloud with Ethical and Legal Implications

Provides a comprehensive overview of wireless computing in medicine, with technological, medical, and legal advances This book brings together the latest work of leading scientists in the disciplines of Computing, Medicine, and Law, in the field of Wireless Health. The book is organized into three main sections. The first section discusses the use of distributed computing in medicine. It concentrates on methods for treating chronic diseases and cognitive disabilities like Alzheimer s, Autism, etc.  It also discusses how to improve portability and accuracy of monitoring instruments and reduce the redundancy of data. It emphasizes the privacy and security of using such devices. The role of mobile sensing, wireless power and Markov decision process in distributed computing is also examined. The second section covers nanomedicine and discusses how the drug delivery strategies for chronic diseases can be efficiently improved by Nanotechnology enabled materials and devices such as MENs and Nanorobots. The authors will also explain how to use DNA computation in medicine, model brain disorders and detect bio–markers using nanotechnology. The third section will focus on the legal and privacy issues, and how to implement these technologies in a way that is a safe and ethical. Defines the technologies of distributed wireless health, from software that runs cloud computing data centers, to the technologies that allow new sensors to work Explains the applications of nanotechnologies to prevent, diagnose and cure disease Includes case studies on how the technologies covered in the book are being implemented in the medical field, through both the creation of new medical applications and their integration into current systems Discusses pervasive computing s organizational benefits to hospitals and health care organizations, and their ethical and legal challenges Wireless Computing in Medicine: From Nano to Cloud with Its Ethical and Legal Implications is written as a reference for computer engineers working in wireless computing, as well as medical and legal professionals. The book will also serve students in the fields of advanced computing, nanomedicine, health informatics, and technology law. INDICE: Contributors xiii .Foreword xvii .Preface xix .PART I INTRODUCTION 1 .1 Introduction to Wireless Computing in Medicine 3Amber Bhargava, Mary Mehrnoosh Eshaghian–Wilner, Arushi Gupta, Alekhya Sai Nuduru Pati, Kodiak Ravicz, and Pujal Trivedi .1.1 Introduction, 3 .1.2 Definition of Terms, 5 .1.3 Brief History of Wireless Healthcare, 5 .1.4 What is Wireless Computing? 6 .1.5 Distributed Computing, 7 .1.6 Nanotechnology in Medicine, 10 .1.7 Ethics of Medical Wireless Computing, 12 .1.8 Privacy in Wireless Computing, 13 .1.9 Conclusion, 14 .References, 14 .2 Nanocomputing and Cloud Computing 17T. Soren Craig, Mary Mehrnoosh Eshaghian–Wilner, Nikila Goli, Arushi Gupta, Shiva Navab, Alekhya Sai Nuduru Pati, Kodiak Ravicz, Gaurav Sarkar, and Ben Shiroma .2.1 Introduction, 17 .2.2 Nanocomputing, 18 .2.3 Cloud Computing, 30 .2.4 Conclusion, 37 .Acknowledgment, 37 .References, 37 .PART II PERVASIVE WIRELESS COMPUTING IN MEDICINE 41 .3 Pervasive Computing in Hospitals 43Janet Meiling Wang–Roveda, Linda Powers, and Kui Ren .3.1 Introduction, 43 .3.2 Architecture of Pervasive Computing in Hospitals, 45 .3.3 Sensors, Devices, Instruments, and Embedded Systems, 49 .3.4 Data Acquisition in Pervasive Computing, 59 .3.5 Software Support for Context–Aware and Activity Sharing Services, 63 .3.6 Data and Information Security, 66 .3.7 Conclusion, 71 .Acknowledgment, 71 .References, 72 .4 Diagnostic Improvements: Treatment and Care 79Xiaojun Xian .4.1 Introduction, 79 .4.2 System Design, 81 .4.3 Body Sensor Network, 82 .4.4 Portable Sensors, 84 .4.5 Wearable Sensors, 88 .4.6 Implantable Sensors, 94 .4.7 Wireless Communication, 95 .4.8 Mobile Base Unit, 97 .4.9 Conclusion and Challenges, 98 .Acknowledgment, 99 .References, 99 .5 Collaborative Opportunistic Sensing of Human Behavior with Mobile Phones 107Luis A. Castro, Jessica Beltran–Marquez, Jesus Favela, Edgar Chavez, Moises Perez, Marcela Rodriguez, Rene Navarro, and Eduardo Quintana .5.1 Health and Mobile Sensing, 107 .5.2 The InCense Sensing Toolkit, 110 .5.3 Sensing Campaign 1: Detecting Behaviors Associated with the Frailty Syndrome Among Older Adults, 119 .5.4 Sensing Campaign 2: Detecting Problematic Behaviors among Elders with Dementia, 123 .5.5 Discussion, 131 .5.6 Conclusions and Future Work, 132 .References, 133 .6 Pervasive Computing to Support Individuals with Cognitive Disabilities 137Monica Tentori, José Mercado, Franceli L. Cibrian, and Lizbeth Escobedo .6.1 Introduction, 137 .6.2 Wearable and Mobile Sensing Platforms to Ease the Recording of Data Relevant to Clinical Case Assessment, 144 .6.3 Augmented Reality and Mobile and Tangible Computing to Support Cognition, 151 .6.4 Serious Games and Exergames to Support Motor Impairments, 158 .6.5 Conclusions, 168 .Acknowledgments, 172 .References, 172 .7 Wireless Power for Implantable Devices: A Technical Review 187Nikita Ahuja, Mary Mehrnoosh Eshaghian–Wilner, Zhuochen Ge, Renjun Liu, Alekhya Sai Nuduru Pati, Kodiak Ravicz, Mike Schlesinger, Shu Han Wu, and Kai Xie .7.1 Introduction, 187 .7.2 History of Wireless Power, 189 .7.3 Approach of Wireless Power Transmission, 191 .7.4 A Detailed Example of Magnetic Coupling Resonance, 194 .7.5 Popular Standards, 199 .7.6 Wireless Power Transmission in Medical use, 201 .7.7 Conclusion, 204 .Acknowledgments, 205 .References, 205 .8 Energy–Efficient Physical Activity Detection in Wireless Body Area Networks 211Daphney–Stavroula Zois, Sangwon Lee, Murali Annavaram, and Urbashi Mitra .8.1 Introduction, 211 .8.2 Knowme Platform, 215 .8.3 Energy Impact of Design Choices, 217 .8.4 Problem Formulation, 228 .8.5 Sensor Selection Strategies, 232 .8.6 Alternative Problem Formulation, 237 .8.7 Sensor Selection Strategies for the Alternative Formulation, 241 .8.8 Experiments, 244 .8.9 Related Work, 254 .8.10 Conclusion, 256 .Acknowledgments, 257 .References, 257 .9 Markov Decision Process for Adaptive Control of Distributed Body Sensor Networks 263Shuping Liu, Anand Panangadan, Ashit Talukder, and Cauligi S. Raghavendra .9.1 Introduction, 263 .9.2 Rationale for MDP Formulation, 265 .9.3 Related Work, 268 .9.4 Problem Statement, Assumptions, and Approach, 269 .9.5 MDP Model for Multiple Sensor Nodes, 272 .9.6 Communication, 274 .9.7 Simulation Results, 276 .9.8 Conclusions, 292 .Acknowledgment, 294 .References, 294 .PART III NANOSCALE WIRELESS COMPUTING IN MEDICINE 297 .10 An Introduction to Nanomedicine 299Amber Bhargava, Janet Cheung, Mary Mehrnoosh Eshaghian–Wilner, Wan Lee, Kodiak Ravicz, Mike Schlesinger, Yesha Shah, and Abhishek Uppal .10.1 Introduction, 299 .10.2 Nanomedical Technology, 301 .10.3 Detection, 303 .10.4 Treatment, 305 .10.5 Biocompatibility, 309 .10.6 Power, 311 .10.7 Computer Modeling, 313 .10.8 Research Institutions, 315 .10.9 Conclusion, 317 .Acknowledgments, 317 .References, 317 .11 Nanomedicine Using Magneto–Electric Nanoparticles 323Mary Mehrnoosh Eshaghian–Wilner, Andrew Prajogi, Kodiak Ravicz, Gaurav Sarkar, Umang Sharma, Rakesh Guduru, and Sakhrat Khizroev .11.1 Introduction, 323 .11.2 Overview of MENs, 324 .11.3 Experiment 1: Externally Controlled On–Demand Release of Anti–HIV Drug Azttp Using Mens as Carriers, 325 .11.4 Experiment 2: Mens to Enable Field–Controlled High–Specificity Drug Delivery to Eradicate Ovarian Cancer Cells, 331 .11.5 Experiment 3: Magnetoelectric Spin on Stimulating the Brain, 339 .11.6 Bioceramics: Bone Regeneration and MNS, 348 .11.7 Conclusion, 351 .References, 353 .12 DNA Computation in Medicine 359Noam Mamet and Ido Bachelet .12.1 Background for the Non–Biologist, 359 .12.2 Introduction, 362 .12.3 In Vitro Computing, 364 .12.4 Computation in Vivo, 370 .12.5 Challenges, 373 .12.6 Glimpse into the Future, 373 .References, 374 .13 Graphene–Based Nanosystems for the Detection of Proteinic Biomarkers of Disease: Implication in Translational Medicine 377Farid Menaa, Sandeep Kumar Vashist, Adnane Abdelghani, and Bouzid Menaa .13.1 Introduction, 377 .13.2 Structural and Physicochemical Properties of Graphene and Main Derivatives, 379 .13.3 Graphene and Derivatives–Based Biosensing Nanosystems and Applications, 382 .13.4 Conclusion and Perspectives, 389 .Conflict of Interest, 390 .Abbreviations, 390 .References, 391 .14 Modeling Brain Disorders in Silicon Nanotechnologies 401Alice C. Parker, Saeid Barzegarjalali, Kun Yue, Rebecca Lee, and Sukanya Patil .14.1 Introduction, 401 .14.2 The BioRC Project, 402 .14.3 Background: BioRC Neural Circuits, 404 .14.4 Modeling Synapses with CNT Transistors, 408 .14.5 Modeling OCD with Hybrid CMOS/Nano Circuits, 410 .14.6 The Biological Cortical Neuron and Hybrid Electronic Cortical Neuron, 411 .14.7 Biological OCD Circuit and Biomimetic Model, 412 .14.8 Indirect Pathway: The Braking Mechanism, 413 .14.9 Direct Pathway: The Accelerator, 414 .14.10 Typical and Atypical Responses, 415 .14.11 Modeling Schizophrenic Hallucinations with Hybrid CMOS/Nano Circuits, 416 .14.12 Explanation for Schizophrenia Symptoms, 416 .14.13 Disinhibition due to Miswiring, 418 .14.14 Our Hybrid Neuromorphic Prediction Network, 418 .14.15 Simulation Results, 419 .14.16 Numerical Analysis of False Firing, 421 .14.17 Modeling PD with CMOS Circuits, 422 .14.18 Modeling MS with CMOS Circuits, 424 .14.19 Demyelination Circuit, 425 .14.20 Conclusions and Future Trends, 426 .References, 428 .15 Linking Medical Nanorobots to Pervasive Computing 431Sylvain Martel .15.1 Introduction, 431 .15.2 Complementary Functionalities, 432 .15.3 Main Specifications for such Nanorobotic Agents (Nanorobots), 433 .15.4 Medical Nanorobotic Agents An Example, 436 .15.5 Nanorobotic Communication Links Allowing Pervasive Computing, 438 .15.6 Types of Information, 439 .15.7 Medical Nanorobotic Agents for Monitoring and Early Detection, 440 .15.8 Medical Nanorobotics and Pervasive Computing Main Conditions that must be met for its Feasibility, 442 .15.9 Conclusion, 443 .References, 444 .16 Nanomedicine s Transversality: Some Implications of the Nanomedical Paradigm 447José J. López and Mathieu Noury .16.1 Introduction, 447 .16.2 Nanomedicine s Promises, 448 .16.3 Analysing Implications of the Nanomedicine Paradigm, 451 .16.4 The Molecular Underpinnings of Nanomedicine s Transversality, 456 .16.5 Nanomedicine as Predictive Medicine, 457 .16.6 Nanomedicine as Personalized Medicine, 460 .16.7 Nanomedicine as Regenerative Medicine, 465 .16.8 Conclusion, 466 .References, 468 .PART IV ETHICAL AND LEGAL ASPECTS OF WIRELESS COMPUTING IN MEDICINE 473 .17 Ethical Challenges of Ubiquitous Health Care 475William Sims Bainbridge .17.1 Introduction, 475 .17.2 A Philosophical Framework, 478 .17.3 Information Deviance, 480 .17.4 The Current Frenzy, 482 .17.5 Genetic Informatics, 485 .17.6 Ubiquitous Information Technology, 489 .17.7 Stasis versus Progress, 492 .17.8 Problematic Ethics, 494 .17.9 Leadership in Science and Engineering Ethics, 496 .17.10 Conclusion, 498 .References, 499 .18 The Ethics of Ubiquitous Computing in Health Care 507Clark A. Miller, Heather M. Ross, Gaymon Bennett, and J. Benjamin Hurlbut .18.1 Introduction, 507 .18.2 Ubiquitous Computing and the Transformation of Health Care: Three Visions, 511 .18.3 Case Study: Cardiac Implanted Electrical Devices, 516 .18.4 Ethical Reflections, 521 .18.5 Conclusions: The Need for Socio–Technical Design, 534 .References, 537 .19 Privacy Protection of Electronic Healthcare Records in e–Healthcare Systems 541Fredrick Japhet Mtenzi .19.1 Introduction, 541 .19.2 Security and Privacy Concerns of EHR in e–Healthcare Systems, 545 .19.3 Privacy Laws and Regulations of EHRs, 547 .19.4 Privacy of EHRs in e–Healthcare Systems, 552 .19.5 Discussion and Conclusion, 558 .19.6 Contributions and Future Research, 559 .References, 561 .20 Ethical, Privacy, and Intellectual Property Issues in Nanomedicine 567Katie Atalla, Ayush Chaudhary, Mary Mehrnoosh Eshaghian–Wilner, Arushi Gupta, Raj Mehta, Adarsh Nayak, Andrew Prajogi, Kodiak Ravicz, Ben Shiroma, and Pujal Trivedi .20.1 Introduction, 567 .20.2 Ethical Issues, 568 .20.3 Privacy Issues, 579 .20.4 IP Issues, 590 .20.5 Conclusion, 596 .Acknowledgments, 596 .References, 596 .PART V CONCLUSION 601 .21 Concluding Remarks 603Zhaoqi Chen, Mary Mehrnoosh Eshaghian–Wilner, Kalyani Gonde, Kodiak Ravicz, Rakshith Saligram and Mike Schlesinger .21.1 Wireless Computing in Health Care, 603 .21.2 Nanomedicine, 606 .21.3 Ethical, Privacy, and Intellectual Property Issues of Nanomedicine and Wireless Computing, 609 .21.4 Conclusions, 610 .Acknowledgments, 610 .References, 610 .Index 613

• ISBN: 978-1-118-99359-0
• Editorial: Wiley–Blackwell
• Encuadernacion: Cartoné
• Páginas: 668
• Fecha Publicación: 19/08/2016
• Nº Volúmenes: 1
• Idioma: Inglés