This new concise textbook provides a practical, up-to-date resource for practitioners responsible for the care of children with oncologic and haematologic disease. It is specifically designed for fellows/residents in paediatric oncology/haematology seeking a systematic approach to these disorders and practising oncologists and haematologists looking for another opinion and an approach to diagnosis and management. The book contains detailed tables, algorithms and flow diagrams for investigation and clinical management. The book begins with an introduction to the general principles of the scientific foundations and treatment of childhood cancers and haematological malignancies. Separate sections are devoted to descriptions of epidemiology, cellular and molecular biology,cancer genetics, immunology, pharmacology and the conduct of clinical trials.For each area of science covered, key original references and reviews are highlighted to direct further reading. For each tumour-specific chapter, the aim will be to integrate diagnostic, biological and therapeutic issues, with the result that the important biological, genetic and pharmacological information will underpin the current rationales for risk stratification and the development of novel therapies. In particular, each chapter includes discussion of: - Introduction including historial perspective - Epidemiology - Clinical presentation (including ‘humiculus’ denoting anatomical frequencies each for presentation and metastases) - Investigation and staging - Treatment (including tables of major findings of group studies and descriptions) - Strategies for follow upand overview of important late effects - Novel therapeutic approaches - Summary and future directions for management.
- ISBN: 978-1-4051-5350-8
- Editorial: Wiley-Blackwell
- Encuadernacion: Cartoné
- Páginas: 448
- Fecha Publicación: 10/09/2010
- Nº Volúmenes: 1
- Idioma: Inglés