Biology of Mycobacterial Lipids covers various topics pertaining to advancements and current research in the field of Mycobacterial lipids, along with significant progress in the area of lipidomics. The book's chapters present comprehensive, yet systematic cutting-edge research, comprising mycobacterial lipid terminologies, classifications, biosynthetic pathways, tools, techniques and functional burgeoning. This unique reference book has contributions from pioneer researchers, experts and eminent veterans from around the globe. It covers groundbreaking work that will bridge the gap on understanding biochemical patterns related to virulence, pathogenesis and resistance and elucidates on new targets for drug design. This book is an important reference source for biomedical scientists, researchers and those in healthcare industries involved in various aspects of mycobacterial diseases. It provides a forum to foster academic exchange between researchers across different areas of mycobacterial research, healthcare workers, and beyond. Covers major biochemical aspects of MTB lipids, nomenclature, structure, classification and metabolic pathways Focuses on recent trends and state-of-the-art technology used in MTB lipids study Includes statistics, bioinformatics and big-data applications, as well as quality control with references to lipidome studies Brings together the functional aspects of MTB lipidome, involvement of lipids in cellular network and signaling, its involvement in virulence and resistance, and host factor manipulations Highlights the discovery of lipid biomarkers for diagnostic and therapeutic interventions using MTB lipidomic Presents lipids at the interface of various other biomolecules with integrative omics aspects INDICE: Section 1. Mycobacterial Lipids1. Nomenclature, structure, and classification2. Metabolic pathways for lipid biosynthesis and breakdown3. Bioactive lipids4. Lipid droplets5. Neutral lipids6. GlycolipidsSection 2. Tools and Techniques to Study Mycobacterial Lipids7. Conventional methods and advance tools and techniques (Mass spectrometry + TLC)8. Novel lipid probes for studying lipid transport and metabolism. Super-resolution microscopy9. Databases and bioinformatics tools. Challenges and opportunities of big data lipidomic10. Quality controlSection 3. Functional Mycobacterial Lipids and Lipidomic11. Membrane and cellular lipidomic. Membrane organization and dynamics12. Mycobacterial lipids in virulence and pathogenesis: Immunological implications of mycobacterial lipids13. Lipid associated networks and pathways: Signalling lipids14. BiomarkersSection 4. Mycobacterial Lipids at Molecular Interface15. Synergy with other omics16. Genome-lipid association17. Integrated proteomics and lipidomic network: Protein-Lipid interaction18. Lipoprotein
- ISBN: 978-0-323-91948-7
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 316
- Fecha Publicación: 01/07/2022
- Nº Volúmenes: 1
- Idioma: Inglés