Bionanocatalysis: From Design to Applications

Biocatalysis has emerged as a sustainable technique, to synthesize valuable commodity chemicals, with wide application in various industrial domains, such as in agriculture, cosmetics, pharmaceuticals, biofuels, biosensors, biofuel cells, biochemicals, and foods. The synergistic integration of bio-catalysis engineering with nanostructured materials, as unique multifunctional carrier matrices, has emerged as a new interface of nano-biocatalysis (NBC). It offers significant considerations for expanding the design and fabrication of robust catalysts at nanoscale, with improved catalytic characteristics for multipurpose bioprocessing applications, expanding the range of applications of immobilized enzymes to any substrate, eg, a solid substrate, or reactions media, eg, a suspension. In addition, nanostructured materials with unique structural, physical, chemical, and functional entities can be designed to mimic the enzyme micro-environment. A fine-tuned enzyme micro-environment offers the possibility of improving enzyme chemo- regio- and stereo- selectivity and specificity. The use of magnetic nanoparticles to immobilize enzymes allows the local control of temperature, isolating medium and biocatalyst temperatures. This book discusses recent advances in nano-biocatalysis, fundamental design concepts, and their applications in a variety of industry sectors. Strategies for immobilizing enzymes onto nanocarriers, made from polymers, silicas, carbons, and metals, by physical adsorption, covalent binding, cross-linking, or specific ligand spacers, are also discussed, as are the advantages, problems, and solutions, derived from the use of non-porous nanomaterials for enzyme immobilization. This is an important reference source for materials scientists and chemical engineers who would like to learn more about how nanobiocatalysts are designed and used. Outlines the major nanocarriers used in nanobiocatalyst design Explores the properties of nanomaterials that make them effective biocatalysits Assesses the challenges of manufacturing nanobiocatalysts on an industrial scale INDICE: PART 1: BASIC PRINCIPLES 1. Nano-biocatalysis - a drive towards applied bio-catalysis 2. Bi- or multi-enzymatic nano-biocatalytic systems 3. Mechanisms of structural and functional coordination between enzymes and nanostructured cues 4. Nanozymes: next wave of artificial enzymes 5. Engineering enzyme micro-environments 6. Advanced computational modeling - tailoring superior biocatalysis 7. Hyperthermia of magnetic nanomaterials: general principles PART 2: PROSPECTIVE NANOCARRIERS TO DESIGN NANO-BIOCATALYSTS 8. Carbon-based nanocarriers for biocatalysis 9. Metal-based nanocarriers for biocatalysis 10. Polymer-based nanocarriers for biocatalysis 11. Silica-based nanocarriers for biocatalysis 12. Magnetic nanocarriers for biocatalysis PART 3: EMERGING BIOPROCESSING APPLICATIONS 13. Nanobiocatalysis for the food industry 14. Nanobiocatalysis for the food industry 15. Nanobiocatalysis for environmental remediation and protection 16. Nanobiocatalysis for fine chemicals, cosmeceuticals, and pharmaceuticals 17. Nanobiocatalysis for therapeutic applications 18. Nanobiocatalysis for biosensors development 19. Nanobiocatalysis for drug delivery 20. Nanobiocatalysis for biofuel cells 21. Nanobiocatalysis for current pilot scale and industrial scale-up applications 22. Nanobiocatalysis for hyperthermia: Applications 23. Future trends in bionanocatalysis

• ISBN: 978-0-323-91760-5
• Editorial: Elsevier Science
• Encuadernacion: Rústica
• Fecha Publicación: 01/06/2023
• Nº Volúmenes: 1
• Idioma: Inglés