Actin Cytoskeleton in Cancer Progression and Metastasis - Part A

Actin Cytoskeleton in Cancer Progression and Metastasis Part A, Volume 355, in the International Review of Cell and Molecular Biology series provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biologyOffers a wide range of perspectives for basic and translational researchDiscusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications INDICE: 1. Actin isoforms in cancer Christophe Ampe 2. Two sides of the coin: the role of WASp in cytotoxic cells and in malignant cells Lisa Westerberg 3. Paxillin family of focal adhesion adaptor proteins in the regulation of cancer cell invasion Chistopher Turner 4. Myosin isoforms as prognostic factors for disease recurrence Elisabeth Letellier 5. Testin and LMCD1: homologous proteins with a different role in cancer-related properties? Leen VanTroys 6. L-plastin: ectopic expression and post-translational modification in cancer Elisabeth Schaffner-Reckinger 7. Profilin: an unexpected regulator of actin and microtubule dynamics. Jessica Henty-Ridilla 8. Actin regulators in cancer progression and metastases - from structure and function to cytoskeletal dynamics Mira Barda-Saad

• ISBN: 978-0-12-821281-3
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 277
• Fecha Publicación: 01/09/2020
• Nº Volúmenes: 1
• Idioma: Inglés