Actin Cytoskeleton in Cancer Progression and Metastasis - Part C

Actin Cytoskeleton in Cancer Progression and Metastasis - Part C, Volume 358 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. New chapters cover Actin isoforms in cancer, Actin cytoskeleton regulators at invadopodia, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and more. Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biologyOffers a wide range of perspectives for basic and translational researchDiscusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications INDICE: 1. Actin isoforms in cancer Christophe Ampe, Gent Uni 2. Actin cytoskeleton regulators at invadopodia Clement Thomas and Gabriele Sakalauskaite 3. Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer Michelle Dawson 4. Mechanics of actin filaments in cancer onset and progress Tafazzoli-Shadpour 5. Novel facets of Glioblastoma invasion Simone Niclou 6. Testin and LMCD1: Homologous proteins with a different role in cancer-related properties Leen VanTroys

• ISBN: 978-0-12-824138-7
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 277
• Fecha Publicación: 01/04/2021
• Nº Volúmenes: 1
• Idioma: Inglés