Carcinogen-driven mouse models of oncogenesis contains a series of protocols written by world-leading experts in the field. Each of these manuscripts provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Among the range of protocols, the following tumor types are treated: lung carcinomas, squamous cell carcinomas of the skin, mammary carcinomas, hapatocarcinomas, colitis-associated neoplasms, fibrosarcomas and oral squamous cell carcinomas. Protocols are provided by renowned experts in the field Detailed description of protocols allowing appropriate reproduction of the models Author notes are included in each protocol providing useful tips and troubleshooting INDICE: 1. Preface - Chemical carcinogenesis in mice as a model of human cancer: Pros and cons Lorenzo Galluzzi 2. MPA/DMBA-driven mammary carcinomas Aitziber Buqué Martinez 3. Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice Isabelle Plante 4. Urethane-induced lung carcinogenesis Silvano Sozzani 5. Methylcholanthrene-induced fibrosarcomas Awen Gallimore 6. BBN-driven bladder carcinomas Janos Terzic 7. Oral squamous cell carcinomas driven by 4NQO Nancy J. Philp 8. Analysing skin tumor development in mice by the DMBA/TPA model Cord Brakebusch 9. DSS/AOM-driven colorectal carcinomas David C. Montrose 10. Diethylnitrosamine-induced liver tumorigenesis in mice Peter Hasselblatt 11. Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice Alison K. Bauer 12. Lung carcinomas induced by NNK and LPS Peter Di 13. Pristane-induced mammary carcinomas Bae Hoon Lee 14. The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis Pierre Saintigny
- ISBN: 978-0-12-822534-9
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 362
- Fecha Publicación: 01/04/2021
- Nº Volúmenes: 1
- Idioma: Inglés