Non-Canonical Autophagy: Mechanisms and Pathophysiological Implications

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between 'canonical' and 'non-canonical' forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of 'non-canonical' autophagy. Non-canonical Autophagy: Mechanisms and Pathophysiological Implications also discusses all the forms 'non-canonical' autophagy and the complexity of autophagy-dependent cell death as the challenges and pitfalls in the development of clinically viable modulators of autophagy. This book aims to give readers a better understanding of mechanisms underlying 'non-canonical' autophagy so that they can interpret biological effects of autophagy correctly and identify reliable novel and effective treatment strategies. Presents the most advanced information regarding the molecular mechanism underlying non-canonical autophagyOutlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processesDiscusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development INDICE: 1. Introduction: canonical vs non-canonical autophagy 2. Overview of Canonical Autophagy  3. Overview of Non-Canonical Autophagy 4. LC3-associated phagocytosis (LAP) 5. Autophagy-dependent cell death (ADCD)  6. Therapeutic targeting of non-conventional autophagy: potential benefits and pitfalls  

• ISBN: 978-0-12-820538-9
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 250
• Fecha Publicación: 01/05/2021
• Nº Volúmenes: 1
• Idioma: Inglés