Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development. Reviews genetic etiology and mechanisms of trisomy 21 Discusses prenatal screening and genetic counseling, including ethical aspects Explores link between Down Syndrome and susceptibility to Alzheimer's and early brain aging Covers cognitive and neurological symptoms and other health consequences Identifies future therapeutic developments INDICE: 1. History and Overview2. Congenital Features and Health Aspects3. Neurobiology of Down Syndrome4. Life-span of Individuals with Down Syndrome5. Prenatal Screening, testing, procedures and Genetic Counseling6. Genetic Cause of Down Syndrome7. Demographic Epidemiology and other Factors8. Research on Down syndrome-related genes9. Sociological and Cultural Aspects of Down syndrome10. Future research
- ISBN: 978-0-323-90456-8
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 200
- Fecha Publicación: 01/08/2022
- Nº Volúmenes: 1
- Idioma: Inglés