Aspartic acid proteases as therapeutic targets

The family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the five major therapeutic targets HIV-1 protease, renin, gamma-secretase, beta-secretase and plasmepsins. A ready reference aimed primarily at professionals in the pharmaceutical industry, as well as for anyone studying proteases and their function.

• ISBN: 978-3-527-31811-7
• Editorial: Wiley-VCH
• Encuadernacion: Cartoné
• Páginas: 606
• Fecha Publicación: 25/08/2010
• Nº Volúmenes: 1
• Idioma: Inglés