P-stereogenic ligands were among the first to be used in asymmetric catalysisbut synthetic difficulties and prejudices have hampered their development. However, continuous screening for new chiral ligands means that they can no longer be ignored and this rigorous reference source reflects their renaissance. The book provides comprehensive coverage of the application of P-stereogenic ligands in homogeneous catalysis. It is divided into two parts and begins with athorough historical introduction to the development of this class of compounds and a complete description of the methods available for their synthesis. Thesecond part deals with the application of these ligands in transition metal catalyzed reactions. It not only discusses the results obtained but also the utility of P-stereogenic ligands in elucidating reaction mechanisms, especially in Rh-catalyzed hydrogenation. The book is filled with many examples from recent primary literature. The synthetic chemist will easily be able to follow thepreparation methods which are accompanied by a description of the challenges and limitations. Those working in homogenous catalysis, and wanting to increase their repertoire of ligands, will be able to establish which have already been used in each reaction and their performance
- ISBN: 978-1-84973-123-2
- Editorial: Royal Society of Chemistry
- Encuadernacion: Cartoné
- Páginas: 267
- Fecha Publicación: 01/12/2010
- Nº Volúmenes: 1
- Idioma: Inglés