This new, thoroughly revised fourth edition is the only current, established and authoritative text focusing on the cellular and molecular physiology of nerve cells. Understanding the functioning of the neuron, the basic cell of the central nervous system requires a clear understanding of the cellular and molecular physiology of the neuron. The book is hypothesis driven rather than just presenting the facts, and the content is firmly based on numerous experiments performed by the top experts in the field. While the book does cover the important facts, it also presents the background for how researchers arrived at this knowledge to provide a context for the field. It teaches not only how excitable cells work in detail, but also how to construct and conduct intelligent research experiments. This book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike. 70% new or updated material in full color throughout, with more than 350 carefully selected and constructed illustrationsFifteen appendices describing neurobiological techniques are interspersed in the textAccompanying Instructor website with exercises and Companion website available INDICE: Part I. Neurons: Excitable and Secretory Cells That Establish Synapses 1. Neurons 2. Neuron - Glial Cell Cooperation 3. Ionic Gradients, Membrane Potential and Ionic Currents 4. The Voltage-Gated Channels of Na+ Action Potentials 5. The Voltage-Gated Channels of Ca+2 Action Potentials: Generalization 6. The Chemical Synapses 7. Neurotransmitter Release Part II. Ionotropic and Metabotropic Receptors in Synaptic Transmission and Sensory Transduction 8. The Ionotropic Nicotinic Acetycholine Receptors 9. The Ionotropic GABAA Receptor 10. The Ionotropic Glutamate Receptors 11. The Metabotropic GABAB Receptors 12. The Metabotropic Glutamate Receptors Part III. Somato-Dendritic Processing and Plasticity of Postsynaptic Potentials 13. Somato-Dendritic Processing of Postsynaptic Potentials I: Passive Properties of Dendrites 14. Subliminal Voltage-Gated Currents of the Somato-Dendritic Membrane 15. Somato-Dendritic Processing of Postsynaptic Potentials II: Role of Subthreshold Depolarizing Voltage-Gated Currents 16. Somato-Dendritic Processing of Postsynaptic Potentials III: Role of High Voltage-Activated Depolarizing Currents 17. Firing Patterns of Neurons 18. Synaptic Plasticity Part IV. The Adult Hippocampal Network 19. The Adult Hippocampal Network 20. Maturation of the Hippocampal Network
- ISBN: 978-0-12-397032-9
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 475
- Fecha Publicación: 15/01/2015
- Nº Volúmenes: 1
- Idioma: Inglés