Bioceramic Coatings for Medical Implants: Trends and Techniques

Reflecting the progress in recent years, this book provides in–depth information on the preparation, chemistry, and engineering of bioceramic coatings for medical implants. It is authored by two renowned experts with over 30 years of experience in industry and academia, who know the potentials and pitfalls of the techniques concerned.Following an introduction to the principles of biocompatibility, they present the structures and properties of various bioceramics from alumina to zirconia. The main part of the work focuses on coating technologies, such as chemical vapor deposition, sol–gel deposition and thermal spraying. There then follows a discussion of the major interactions of bioceramics with bone or tissue cells, complemented by an overview of the in–vitro testing methods of the biomineralization properties of bioceramics. The text is rounded off by chapters on the functionalization of bioceramic coatings and a look at future trends.As a result, the authors bring together all aspects of the latest techniques for designing, depositing, testing, and implementing improved and novel bioceramic coating compositions, providing a full yet concise overview for beginners and professionals. INDICE: PREFACE.BIOMATERIALS –.A HISTORICAL PERSPECTIVE.THE NATURE OF BIOCERAMIC MATERIALS.SCOPE AND SOCIOECONOMIC ASPECTS OF BIOCERAMICS.Europe.USA and Canada.Asia.PRINCIPLES OF BIOCOMPATIBILITY.Bioinert Ceramics.Biotolerant Ceramics.Bioactive Ceramics.Osseoconduction vs. Osseoinduction.HIERARCHICAL STRUCTURE OF BONE TISSUE.FUNDAMENTALS OF INTERACTION OF BIOCERAMICS AND LIVING MATTER.Tissue Level.Cellular Level.STRUCTURE AND PROPERTIES OF SELECTED BIOCERAMICS.Bioinert Ceramics: Alumina, Zirconia, Titania, and Others.Bio(osseo)conductive Ceramics: Bioglasses, Hydroxyapatite, Tricalcium Phosphates, Tetracalcium Phosphate, Transition–Metal Substituted Calcium Orthophosphates, Resorbable Calcium Phosphates, Composite Materials, and Others.TECHNOLOGY OF COATING DEPOSITION.Biomimetic Route.Sol–Gel Deposition.Dip Coating.Electrochemical Deposition.Electrophoretic Deposition.Chemical Vapor Deposition (CVD).Ion Implantation.Magnetron Sputtering.Plasma Electrolytic Oxidation (PEO).Micro–Arc Oxidation (MAO).Laser Cladding.Thermal Spraying (APS, HVOF, PLD, etc.).Suspension Plasma Spraying (SPS).Cold Gas Dynamic Spraying (CGDS).Others.STRUCUTRE, PROPERTIES, AND BIOLOGICAL FUNCTION OF BIOCERAMIC COATINGS.In Vitro Behavior.In Vivo Behavior.IN VITRO TESTING BIOMINERALIZATION PROPERTIES OF BIOCERAMIC COATINGS.Composition of Solutions Mimicking Human ECF (Extracellular Fluid).Biomineralization by Immersion in ECF–Simulating Solutions.Cell Proliferation, Spreading, Vitality and Differentiation Studies.ISO–10993 Standard Testing.Alkaline Phosphatase (ALP) Assay Using ELISA.Osteocalcin Secretion.Osteopontin and Osteonectin Assays.Others.CHEMICAL AND BIOLOGICAL FUNCTIONALIZATION OF BIOCERAMIC COATINGS.FUTURE DEVELOPMENT AND OUTLOOK.

• ISBN: 978-3-527-33743-9
• Editorial: Wiley VCH
• Encuadernacion: Cartoné
• Páginas: 496
• Fecha Publicación: 25/03/2015
• Nº Volúmenes: 1
• Idioma: Inglés