Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more. Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels. Presents the latest volume in the Current Topics in Membranes series, with a novel focus on smooth muscle and endothelial cells in the peripheral microcirculationProvides authoritative contributions from an international team of leading experts actively studying the microcirculationIncludes a unique focus on regional heterogeneity in ion channel expression and function in the peripheral microcirculation INDICE: 1. Introduction to Ion channels and calcium signaling in the microcirculation William F. Jackson 2. Smooth muscle BKCa channels, IP3 Receptors, Voltage-gated Ca2+ channels and the regulation of myogenic tone in striated muscle arterioles William F. Jackson 3. Endothelial Kir channels as a key component of shear stress-induced mechanotransduction Irena Levitan 4. Endothelial TRPV4 channels and vasodilator reactivity Swapnil K. Sonkusare 5. TRPA channels in cerebral capillary endothelial cells and regulation of flow Scott Earley 6. Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension Anne Dorrance 7. Ion channels and myogenic tone development in the retinal microcirculation Tim Curtis 8. KIR Channels in the Microvasculature: From Basis Properties and Dynamic Regulation by Lipid and Hemodynamic Forces Donald Welsh 9. Ion channels and calcium signaling in capillary endothelial cells Thomas Longden 10. Excitability and Contractility in Arterioles and Venules from the Urinary Bladder Nathan R. Tykocki 11. Intrinsic regulation of microvascular tone by myoendothelial feedback circuits Kim Dora
- ISBN: 978-0-12-820090-2
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 310
- Fecha Publicación: 01/06/2020
- Nº Volúmenes: 1
- Idioma: Inglés