RNA interference: application to drug discovery and challenges to pharmaceutical development

RNA interference: application to drug discovery and challenges to pharmaceutical development

Johnson, Paul H.

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INDICE: CONTRIBUTORS. PREFACE. FOREWORD. I. Biology of RNA Interference. 1 RNA Interference: What is it? (James A. Birchler). 2 Nucleic Acids as Regulatory Molecules (Faqing Huang, C. J. Yu, and Yanlin Guo). 3 Use of siRNA Oligonucleotides to Study Gene Function (Kristin A. Wiederholt and Adam N. Harris). 4 Genome Scanning by RNA Interference (Roderick L. Beijersbergen and Oliver C. Steinbach). II Development of siRNA for Therapeutic Applications. 5 Discovery of New siRNA Delivery Agents (Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay). 6 siRNA Delivery Vehicles (Aliasger K. Salem and Mark A. Behlke). 7 Interferon, Cytokine Induction and Other Potential In Vivo Toxicities (Adam Judge, Marjorie Robbins, and Ian MacLachlan). 8 Application of RNA Interference to Viral Diseases (Ralph A. Tripp and Stephen Mark Tompkins). Index.

  • ISBN: 978-0-471-77151-7
  • Editorial: John Wiley & Sons
  • Encuadernacion: Cartoné
  • Páginas: 332
  • Fecha Publicación: 07/01/2011
  • Nº Volúmenes: 1
  • Idioma: Inglés