Eight-Membered Heterocycle Synthesis focuses on both new and established methods for the synthesis of various eight-membered heterocycles. Covering an important and rapidly growing branch of heterocyclic chemistry, this book brings together every protocol for the synthesis of eight-membered heterocycles in one place, allowing readers to see all possibilities for making a particular compound using one particular reagent. The book provides updated and comprehensive information about the synthesis of medium-ring heterocycles, with easy access to the synthetic protocols for different eight-membered heterocycles, case studies, and applications. The book is essential reading for students, researchers, pharmacologists, biochemists, and organic and medicinal chemists. Covers the different methodologies for the synthesis of eight-membered heterocycles Includes summary schemes for each type of heterocycle, giving an overview of all the reactants that can be used, and the experimental conditions Includes discussion of the applications of eight-membered heterocycles INDICE: 1. Synthesis of azocines 2. Synthesis of azocines by diene metathesis 3. Synthesis of azocines by ring-expansion 4. Synthesis of azocines and diazocines from amine containing alkenes and alkynes 5. Synthesis of diazocines 6. Synthesis of diazocines and oxocines by cyclization of dienes 7. Synthesis of diazocines and oxocines by ring-contraction and -expansion 8. Synthesis of azocines and oxocines by ring-closure of halo, amine and oxo compounds 9. Synthesis of oxocines 10. Synthesis of oxazocines 11. Synthesis of thiocines and thiazocines References
- ISBN: 978-0-323-95652-9
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 650
- Fecha Publicación: 01/02/2023
- Nº Volúmenes: 1
- Idioma: Inglés