Imines to azetidines by cycloaddition presents detailed information about the synthesis of azetidines from imines by cycloaddition reactions. The synthesis of azetidines is a constant challenge for medicinal chemists, and this book that comprehensively describes azetidine ring synthesis. The readers are able to quickly assess the possible synthetic approaches, and evaluate whether preparation of a four-membered nitrogen containing ring is reasonable. The formation of heterocycles has always attracted attention over the years due to their important medicinal properties. This book presents several methodologies for the synthesis of azetidines from imines by cycloaddition reactions and the readers will defiantly gain knowledge about the topic. The azetidines, known as important contribution of science to humanity are important organic compounds and occupy a basic position in pharmaceutical chemistry for over hundred years now because of their biological activities. They are the fundamental skeleton of several antibiotics, probiotics, and alkaloids. Highlights cycloaddition reactions of imines Covers synthesis of azetidines INDICE: 1. Synthesis of azetidines from imines 2. Synthesis of azetidines by cycloaddition of imines to alkenes 3. Synthesis of azetidines by metal-catalyzed cycloaddition of imines to alkenes 4. Synthesis of azetidines by cycloaddition of imines to ketenes-I 5. Synthesis of azetidines by cycloaddition of imines to ketenes-II 6. Synthesis of azetidines by cycloaddition of imines to carbonyl compounds 7. Synthesis of azetidines by cycloaddition of imines to acetyl chloride moiety 8. Synthesis of azetidines by cycloaddition of imines to aromatic acetyl chloride moiety 9. Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-I 10. Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-II
- ISBN: 978-0-443-19204-3
- Editorial: Elsevier
- Encuadernacion: Rústica
- Fecha Publicación: 01/01/2023
- Nº Volúmenes: 1
- Idioma: Inglés