Protein kinases as drug targets

Protein kinases as drug targets

Klebl, Bert
Müller, Gerhard
Hamacher, Michael

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INDICE: INTRODUCTION Signal transduction Inhibitors HIT FINDING AND PROFILING In vitro characterization of small molecule kinase inhibitors Cellular Kinase Inhibition CHEMICAL GENOMICS Dissecting phosphorylation networks: the use of analogue sensitive kinases and more specific kinase inhibitors as tools MEDICINAL CHEMISTRY Compendium of small molecule kinase inhibitors Kinase Inhibitor Lead Technologies Design Principles of Deep Pocket targeting protein kinase inhibitors KINASE INHIBITOR THERAPY Discovery and Design of Protein Kinase Inhibitors: Targeting the cell cycle in Oncology From Discovery to Clinic: AuroraKinase Inhibitors as Novel Treatments for Cancer Medicinal Chemistry Approaches for the Inhibition of the p38 MAPK Pathway Cellular Protein kinases as antiviral targets Infectious Diseases

  • ISBN: 978-3-527-31790-5
  • Editorial: Wiley-VCH
  • Encuadernacion: Cartoné
  • Páginas: 390
  • Fecha Publicación: 09/02/2011
  • Nº Volúmenes: 1
  • Idioma: Inglés