Cardiac mechano-electric coupling and arrhythmias

Ranging from stretch-activated ion channels to mechanically induced arrhythmias and mechanical interventions for heart rhythm correction, this new edition offers a thoroughly reviewed compendium of chapters, written by the top-experts in the world, on the mechanism and consequences of cardiac mechano-electrical coupling. INDICE: Basic Science, Section I: Sub-Cellular Mechanisms of Cardiac Mechano-Electric Coupling; 1: Boris Martinac and Anna Kloda: Evolutionary origins of stretch-activated ion channels; 2: Frederick Sachs: SACs in the heart; 3: Eric Honoré and Amanda Patel: The mechano-gated K2P channel TREK-1 in the cardiovascular system; 4: Clive M. Baumgarten, Wu Deng, and Frank J. Raucci, Jr. Cell VolumeDSSensitive Ion Channels and Transporters in Cardiac Myocytes; 5: Gentaro Iribe and Peter Kohl: Non-sarcolemmal stretch-activated channels; 6: Catherine E. Morris: Pacemaker, potassium, calcium, sodium: stretch modulation of the voltage-gated channels; 7: Sarah Calaghan: Role of caveolae in stretch-sensing: implications for mechanoelectric coupling; 8: Thomas M. Suchyna and Frederick Sachs: The membrane/cytoskeleton interface and stretch-activated channels; 9: Michiel Helmes and Henk Granzier: Cardiomyocyte stretch sensing; 10: JohnJeremy Rice and Donald M. Bers: The response of cardiac muscle to stretch: Calcium and force; 11: Jean-Luc Balligand and Chantal Dessy: Stretch effects on second messengers; 12: Kevin Kit Parker: Functional implications of Myocyte Architecture; Basic Science, Section II: Cellular Manifestations of Cardiac Mechano-Electric Coupling; 13: Patricia J. Cooper and Ursula Ravens: Mechanical modulation of pacemaker electrophysiology; 14: Michael R. Franz: Mechano-electric coupling in working cardiomyocytes: diastolic and systolic effects; 15: Chang Ahn Seol, Won Tae Kim, Jae Boum Youm, Yung E. Earm, and Chae Hun Leem: Mechano-sensitivity of pulmonary vein cells: implications for atrial arrhythmogenesis; 16: Henk E.D.J. ter Keurs, Ni Diao, Nathan P. Deis, Mei L Zhang, Yoshinao Sugai,. Guy Price, Yuji Wakayama, Yutaka Kagaya, Yoshinao Shinozaki, Penelope A Boyden, Masahito Miura, Bruno DM Stuyvers: Heterogeneity of sarcomere lengthand function as a cause of arrhythmogenic calcium waves; 17: Kenneth R. Laurita: Cellular mechanisms of arrhythmogenic cardiac alternans; 18: André G. Kléber and Jeffrey E. Saffitz: Remodeling of gap junctions in ventricular myocardium: Effects of cell-to-cell adhesion, mediators of hypertrophy and mechanical forces; 19: Troy A. Baudino and Thomas K. Borg: The origin of fibroblasts, ECMand potential contributions to cardiac mechano-electric coupling; 20: Leslie Tung and Susan A. Thompson: Advantages and pitfalls of cell cultures as model systems to study cardiac mechanoelectric coupling; Basic Science, Section III:Multi-cellular manifestations of mechano-electric coupling; 21: Vladimir S. Markhasin, Alexander Balakin, Yuri Protsenko, and Olga Solovyova: Activation sequence of cardiac muscle in simplified experimental models: Relevance for cardiac mechano electric coupling; 22: Peter Kohl: ; 23: Michael R. Franz and Frank Bode: Acute stretch effects on atrial electro-physiology; 24: Christian Bollensdorff and Max J Lab: Stretch effects on potassium accumulation and alternans in pathological myocardium; 25: Ro

• ISBN: 978-0-19-957016-4
• Editorial: Oxford University
• Encuadernacion: Cartoné
• Fecha Publicación: 01/05/2011
• Nº Volúmenes: 1
• Idioma: Inglés