This book is written by experts in the field of hematopoietic stem cell biology and lymphocyte development in order to overview recent advances in the field. Prospective isolation of various progenitors and stem cells enables us to understand self-renewal mechanisms of stem cells as well as regulation of hematopoiesis. Furthermore, the importance of extrinsic factors has been emphasizedrecently. This volume concisely describes our current understanding of normalhemato/lymphopoiesis as well as abnormal hematopoiesis, which may lead to leukemia. Each chapter is precisely described by the expert in the field Will provide a basic information of hematopoietic stem cell and its differentiation asa prototype of the Stem Cell Biology Clinical relevance of the biology of thehematopoietic stem cells is also provided INDICE: List of Contributors. Acknowledgement. Preface. 1 Principles of hematopoietic Stem Cell Biology. 2 Hematopoietic Stem Cells and Their Niche. 3 Hematopoietic Stem Cells and Somatic Stem Cells. 4 Developmental Biology of Mammalian T cell progenitors: From Early Lymphoid Progenitors to Thymus-Colonizing Cells. 5 GATA-1 and GATA-2 functions in hematopoietic differentiation. 6 Role of the IL-7 Receptor in T Cell Development from Hematopoietic Stem Cells. 7 Dendritic cell homeostasis – physiology and impact on disease. 8 Wnt in hematopoietic and leukemic stem cells.
- ISBN: 978-1-60327-346-6
- Editorial: Humana
- Encuadernacion: Cartoné
- Páginas: 448
- Fecha Publicación: 01/12/2009
- Nº Volúmenes: 1
- Idioma: Inglés