Opioids Addiction
Koob, George F.
Arends, Michael A.
McCracken, Mandy
Le Moal, Michel
A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids Addiction, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction. This volume introduces the readers to the history of opioid use including the medical uses of opioids. The authors clearly define the neurobiological effects into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage and last the Preoccupation/Anticipation Stage. Highlights recent advances in opioid addictionIncludes Neurocircuitry, Cellular and Molecular neurobiological mechanisms of opioid addictionDefines opioid abuse and addiction potential including biological tolerance INDICE: 1. Definitions 2. History of opioid use 3. Mechanism of action: endogenous opioid system 4. Physiological effects 5. Behavioral effects 6. Pharmacokinetics 7. Behavioral mechanism of action 8. Medical use, abuse, and addiction 9. Neurobiological effects 10. Summary
- ISBN: 978-0-12-816988-9
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 350
- Fecha Publicación: 01/07/2021
- Nº Volúmenes: 1
- Idioma: Inglés