Albinism in Africa: Historical, Geographic, Medical, Genetic, and Psychosocial Aspects

With Albinism in Africa Drs. Jennifer Kromberg and Prashiela Manga have assembled the first in-depth reference for understanding and treating patients of human albinism in Africa. Leading international contributors examine the historical, geographic, psychosocial, genetic, and molecular considerations of importance in effectively and sensitively managing this genetic disorder, providing researchers, clinicians, genetic counselors, and public health workers with the necessary background to counsel and care for stigmatized patient populations. Foundational chapters covering the historical and psychosocial aspects of albinism are supplemented by discussions of the pathobiology of the disease, as well as thorough analysis of the genetics of skin pigmentation, eye pigmentation, hair pigmentation, and skin cancer involved in manifestations of the disorder. New prenatal diagnostics and genetic testing methods; genetic risk assessment for individuals, families, and communities; and novel genetic markers that may be used for developing new therapeutics for treating albinism, are also discussed in detail. In Albinism in Africa, readers will discover thoughtfully considered care management approaches that may be applied to instances of albinism in other regions, along with guiding principles for treating rare genetic disorders and stigmatized patient populations across the globe. Leading international contributors examine the historical, geographic, psychosocial, genetic, and molecular aspects of importance in sensitively managing albinism in Africa, providing researchers, clinicians, genetic counselors, and public health workers with the necessary background to counsel and care for stigmatized patient populationsDiscusses recent advances in our understanding of the pathobiology of albinism, and offers thorough analysis of the genetics of skin pigmentation, eye pigmentation, hair pigmentation, and skin cancer involved in manifestations of albinismHighlights new prenatal diagnostics and genetic testing methods; approaches to genetic risk assessment for individuals, families, and communities; and novel genetic markers that may be used for developing new therapeutics for albinismProvides care management approaches that may be applied to instances of albinism in other regions, along with guiding principles for treating other rare genetic disorders and stigmatized patient populations across the globe INDICE: 1. Introduction and historical background2. Clinical features, types of albinism and natural history3. Epidemiology of albinism 4. Medical aspects. Dermatology5. Medical aspects. Ophthalmology6. Psychosocial aspects of albinism 7. Molecular biology of albinism 8. Genetic Counselling 9. Genetic testing and prenatal diagnosis 10. Management and therapy 11. Conclusion

• ISBN: 978-0-12-813316-3
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 300
• Fecha Publicación: 02/01/2018
• Nº Volúmenes: 1
• Idioma: Inglés