Variety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the environment as well as inside the host and adapt number of strategies for their survival. In 5 parts Bacterial Survival in the Hostile Environment covers all tactics and strategies adopted by bacteria for their survival under stressed conditions and will be focused on mechanistic insights of pathogenic adaptations to host environments (acidic environment, microaerobic conditions, immune system stress, metal stress etc., modulation of host pathways by pathogens for survival, dormancy, drug tolerance and resistance, proteins for stress survival). The content also includes different adaptation mechanisms of extremophiles to extreme environment, provides a complete and globally available advance knowledge related to bacterial survival from different perspectives and reviews the knowledge gaps and future prospects in the field of microbial adaptation for sustainable development of in the field of infection biology and pharmaceutics. Provides in depth knowledge about pathogen biology and microbial adaptations, microbe-host interactions, impact of pathogens on host physiology, virulent factors produced by pathogens and pharmaceutical applications, mechanism of pathogenic virulent factors Covers all tactics and strategies adopted by bacteria for their survival under stressed conditions Focuses on mechanistic insights of pathogenic adaptations to host Includes different adaptation mechanisms of extremophiles to extreme environment INDICE: Part 1: 1. Pathogenic adaptation to host environment 2. Adaptation to acidic environment 3. Microaerobic conditions 4. Immune system stress 5. Metal stress Part 2: Modulation of host pathways by pathogens for adaptation/survival 6. Modulation in glycolytic flux 7. Endoplasmic reticulum stress 8. Host Mitochondria 9. Apoptosis 10. Necrosis 11. Phagosome maturation 12. Autophagy regulation Part 3: Dormancy, Drug Tolerance and Resistance 13. Growth regulation by microbes 14. Survival and reactivation strategies of pathogens in stress through heterogeneous population generation 15. Persisters 16. Antimicrobial resistance Part 4: Proteins for stress survival 17. Chaperones 18. Ribosome associated proteins 19. Methyltransferases 20. Proteins responsible for growth regulation of bacteria during unfavourable conditions 21. Proteins involved in biofilm Part 5: Adaptation to Extreme Environment 22. Adaptations to Ph 23. Temperature 24. Pressure 25. Halophilic adaptations 26. Radiation adaptation
- ISBN: 978-0-323-91806-0
- Editorial: Academic Press
- Encuadernacion: Rústica
- Fecha Publicación: 01/09/2022
- Nº Volúmenes: 1
- Idioma: Inglés