The Genomic and Molecular Cardiovascular Medicine

The Genomic and Molecular Cardiovascular Medicine largely focuses on pertinent genomic and molecular aspects of cardiovascular medicine relevant to all levels of clinical practice, from primary care to preventive healthcare. The book also focuses on practice applications of translational genomic and molecular developments and advances that impact on cardiovascular system structure and function. Each chapter is evidence-based and comprehensive, with in-depth, cutting-edge knowledge relevant to the practice of clinical cardiology and cardiovascular surgery. The book aims to fill a major gap of knowledge resource focused on genomic and molecular aspects of contemporary cardiovascular medicine and surgery practice. In view of scientific and technical complexities of the field, the book is written by a team of globally acknowledged experts in respective clinical, investigative, therapeutic and preventive aspects. The current practices within cardiovascular medicine and surgery offer excellent opportunity for genomic and molecular applications to achieve the high order effectiveness with maximum efficiency. Includes clinical applications of genomic and molecular new knowledge, along with advances in the practice of cardiovascular medicine and surgery Provides wide coverage of all major clinical and preventive aspects of clinical cardiology, including multi-disciplinary team care Focuses on targeted gene and molecular therapy in clinical cardiovascular medicine and surgery INDICE: 1. Introduction to genomic and molecular biology2. Methods in genomic and molecular medicine3. Structure and function of the cardiovascular system4. Molecular embryology of the cardiovascular system5. Molecular mechanisms of cardiac electrical generation, conduction and regulation6. Ion channel genomics and proteomics7. Molecular structure and function of the myocardium8. Molecular correlations of the myocardium with skeletal and smooth muscles9. Genetic and molecular basis of metabolic and nutritional cardiovascular regulation10. Genetic and molecular pathophysiology of heart failure11. Molecular aspects of arterial, venous and lymphatic circulation12. Molecular mechanisms and pathophysiology of pulmonary arterial and venous hypertension13. Molecular perspectives of the cardiovascular inflammation14. Molecular mechanisms of cardiovascular system response to hyperlipidemia and hyperglycemia15. Molecular pathology of coronary (ischemic) artery disease (CAD)16. Molecular basis of the adverse drug and toxin response of the cardiovascular system17. Precision and personalise cardiovascular medicine including Molecular cardiovascular therapeutics18. Novel cellular and molecular cardiovascular therapeutics19. Genomic and Molecular basis of cardiovascular phenotype ontology20. Preventive and public health applications of the genomic and molecular cardiovascular medicine (including social, ethical and legal aspects)21. Glossary- selection and explanation of pertinent terms & phrases

• ISBN: 978-0-12-822951-4
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 360
• Fecha Publicación: 01/01/2023
• Nº Volúmenes: 1
• Idioma: Inglés