Water and biomolecules: physical chemistry of life phenomena

Life is produced by the interplay of water and biomolecules. This book deals with the physicochemical aspects of such life phenomena produced by water and biomolecules, and addresses topics including Protein Dynamics and Functions, Protein and DNA Folding, and Protein Amyloidosis. All sections have been written by internationally recognized front-line researchers. The idea for this bookwas born at the 5th International Symposium Water and Biomolecules, held in Nara city, Japan, in 2008. Deals mainly with the interplay of water and biomolecules, to a large part with protein folding and related aspects Gives a comprehensive state-of-the-art report on the latest results of research on biomolecules in water A valuable reference for researchers INDICE: From the contents 1. Mapping Protein Folding Landscapes by NMR Relaxation.- 2. Experimental and Simulation Studies on the Folding/Unfolding of Goat a-Lactalbumin.- 3. Transition in the Higher-order Structure of DNA in Aqueous Solution.- 4. Generalized-Ensemble Algorithms for Studying Protein Folding.- 5. Protein Folding and Binding: Effective Potentials, Replica Exchange Simulations, and Network Models.- 6. Functional Unfolded Proteins: How, When, Where and Why?.- 7. Structure of the Photointermediate of Photoactive Yellow Protein and the Propagation Mechanism of Structural Change.- 8. Time-resolved Detection of Intermolecular Interaction of Photosensor Proteins.- 9. Volumetric Properties of Proteins and the Role of Solvent in Conformational Dynamics.- 10. AStatistical Mechanics Theory of Molecular Recognition.- 11. Computational Studies of Protein Dynamics.- 12. Biological Functions of Trehalose as a Substitute for Water.

• ISBN: 978-3-540-88786-7
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 360
• Fecha Publicación: 01/04/2009
• Nº Volúmenes: 1
• Idioma: Inglés