Visceral and Ectopic Fat: Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease

While the health consequences and mechanisms by which visceral fat causes disease are well-studied, relatively less is known about ectopic fat, its patterns of deposition and its effects on the pathoetiology of type 2 diabetes, atherosclerosis, and cardiovascular disease. Visceral and Ectopic Fat: Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease covers the wealth of literature that has been amassed over the past decade on this topic. This reference brings all the research and clinical data together in one volume and helps clinicians and academic researchers understand more thoroughly the underlying mechanisms and interrelation between fat depots and ectopic fat stores in relation to health and disease. It showcases some of the recent developments in adipose tissue biology, particularly on the impact of interventional strategies - bariatric surgery, liposuction, physical and dietary intervention - of which information is desired among health specialists and policy makers. Brings together up-to-date research on imaging, genetics, and risk factors for chronic diseases such as diabetes, heart disease, cancer, and fatty liver disease Takes a deep dive into the current state of knowledge regarding fat stores, ectopic fat, regulation of fat stores, clinical implications, interventions, and imagining techniques Provides up-to-date information specifically focused on visceral and ectopic fat. In addition, both pathophysiological and preventive and treatment aspects of the problem will be considered Covers a broad range of organs - different fat stores such as skeletal muscle, bone marrow, liver and kidney Discusses potential interventions to reduce abdominal fat INDICE: Part I: Fat Stores1. Obesity/VAT/SAT/Sex specific2. Obesity and fat distribution in children and adolescents3. Brown Adipose Tissue4. Pericardial and peri-coronary fatPart II: Ectopic fat stores5. Noninvasive profiling of ectopic lipids6. Flexibility of ectopic lipids7. Liver8. Myocardial Lipids - Techniques and Applications of Proton Magnetic Resonance Spectroscopy of the Human Heart9. Pancreas ectopic fat: imaging-based quantification10. Ectopic fat accumulation around and within the kidney11. Skeletal muscle12. Bone marrow adipose tissuePart III: Regulation of fat stores13. Endocrinological pathways14. The role of inflammation of fat tissue in relation to obesitasPart IV: Clinical Aspects15. Role of adipose tissue remodelling in diabetic heart disease16. Cardiovascular Disease 17. Obesity in Relation to Cardiorenal function18. Lung/Asthma19. Brain AtrophyPart V: Interventions20. The impact of Very Low-Calorie Diets on ectopic fat deposition21. Intermittent Fasting22. Exercise23. Combined Lifestyle Intervention24. Medical Therapy25. Gastric Volume Reduction26. Gastric Bypass27. Fecal Transplant

• ISBN: 978-0-12-822186-0
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 350
• Fecha Publicación: 01/10/2022
• Nº Volúmenes: 1
• Idioma: Inglés