Pharmacogenomics is the process of analyzing patients' genes to predict the onset of adverse reactions or forecast the effectiveness of therapeutic drugs. This useful text is written to discuss both the theory and the clinical application of the principles of pharmacogenomics. Current research has clearly established that a range of treatments may be greatly improved through genetic profiling of individual patients before certain therapies begin. Aimed at clinicians, pharmacologists, and clinical laboratory professionals this book discusses the important role of laboratory tests in the practice of personalized medicine. An important new book, Pharmacogenomics in Clinical Therapeutics serves as a guide to the basic principles of pharmacogenomics in a range of common therapeutic areas and as the basis of the personalized medicine of the future. INDICE: List of Contributors, viiPreface, ix1 Pharmacogenomics Principles:Introduction to Personalized Medicine, 1Parvaz Madadi, PhD and Gideon Koren, MD2 Traditional Therapeutic Drug Monitoring and Pharmacogenomics: Are They Complementary? 15Christine L.H. Snozek, PhD, Loralie J. Langman, PhD, and AmitavaDasgupta, Ph.D3 Pharmacogenomics Aspect of Warfarin Therapy, 26Matthew D. Krasowski, MD, PhD4 Pharmacogenetics and Cancer Chemotherapy, 39Christine L.H. Snozek5 Pharmacogenomic Considerations in Anesthesia and Pain Management, 53Christine M. Formea, PharmD and Wayne T. Nicholson, MD, PharmD6 Pharmacogenomics of Immunosuppressants, 70Nicolas Picard, PharmD, PhD and Pierre Marquet, MD, PhD7 Pharmacogenomics of Cardiovascular Drugs, 98Linnea M. Baudhuin, PhD8 Pharmacogenomic Aspects of Antiretroviral Therapy, 127Natella Y. Rakhmanina, MD, PhDand John N. van den Anker, MD, PhD9 Pharmacogenetics of Psychoactive Drugs, 144Jorge L. Sepulveda, MD, PhD10 Pharmacogenomic Aspects of Adverse Drug-Drug Interactions, 176Loralie J. Langman, PhD and Christine L.H. Snozek, PhD11 Microarray Technology and Other Methods in Pharmacogenomics Testing, 185Jorge L. Sepulveda, MD, PhD12 Pharmacogenetic Testing in the Clinical Laboratory Environment, 201Mark P. Borgman, PhD and Mark W. Linder, PhDIndex, 225
- ISBN: 978-1-119-95960-1
- Editorial: John Wiley & Sons
- Encuadernacion: Rústica
- Páginas: 400
- Fecha Publicación: 27/03/2012
- Nº Volúmenes: 1
- Idioma: Inglés