In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design

In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body's ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body's own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. Explores the body's ability to mobilize endogenous stem cells to the site of injury Details the latest strategies developed for inducing and supporting the body's own regenerating capacityPresents smart biomaterials in cell-based tissue engineering applications-from the cell level to applications-in the first unified volumeFeatures chapter authors and editors who are authorities in this emerging fieldPrioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry INDICE: 1. Fundamentals of In Situ Tissue Regeneration PART 1: Endogenous Cell Sources 2. Stem Cell Homing 3. Tissue-Specific Stem Cells/Progenitor Cells 4. Direct Differentiation; In Vivo Reprogramming 5. Immunology - Host Responses to Biomaterials 6. Biochemical and Physical Cues 7. Stem Cell Inducing Factors 8. Chemoattractants 9. Gene Delivery 10. Biomaterial Topography PART 2: Smart Biomaterial Development 11. Self-Assembling Peptides 12. Peptide Nanomaterials 13. Functionalized Polymeric Biomaterials 14. Scaffold Design/Drug Delivery System 15. Tissue-Derived Matrices PART 3: Applications 16. Nerve System 17. Bone/Cartilage 18. Cartilage 19. Bone 20. Dental 21. Volumetric Muscle Repair 22. Skeletal Muscle Development 23. Blood Vessel 24. Heart: Myocardium 25. Skin/Wound Healing 26. Liver 27. Renal Regeneration

• ISBN: 978-0-12-802225-2
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 442
• Fecha Publicación: 01/08/2016
• Nº Volúmenes: 1
• Idioma: Inglés