Prion Protein, Volume 150, the latest volume in the Progress in Molecular Biology and Translational Science focuses on Prion Protein. Neurodegenerative diseases represent a health issue that in recent years has received increasing attention from the scientific community due to their social and economic impact. In particular, prion protein is considered to be the archetype of intrinsically disordered proteins that, upon misfolding, are prone to adopt aberrant conformations. Nevertheless, the molecular events underlying the onset and the progression of these diseases (misfolding, spreading, plaques formation, neuronal death) are still largely unknown. Presents the latest volume in the Progress in Molecular Biology and Translational Science seriesAccessible to students and researcher alikeWritten by leading authorities in the field of prion protein INDICE: Functions of Prion ProteinSophie Mouillet-RichardCopper and Prion proteinGlenn MillhauserCell Biology of Prion ProteinChiara Zurzolo and Daniela Sarnataro Structural Studies of Prion ProteinsJanez PlavecMolecular Simulations on Wild Type and Mutant Prion ProteinsPaolo CarloniGenetics of Prion ProteinGeorge A. CarlsonThe Prion Concept and Synthetic PrionsGiuseppe Legname and Silvia Vanni Transgenic Mouse ModelsAbigail DiackTransmission and Replication of PrionsJuan Maria TorresImmunology of Prion Protein and PrionsNeil Andrew MabbottBSE, BASECristina Casalone and Corona Cristiano Scrapie, CDW and Trasmissible Mink EncephalopathyCandace MathiasonInfectious and Sporadic Prion DiseasesRichard KnightInhereted Prion DiseasesBernardino GhettiNeuropathology of Prion DiseasesJames Wilson Ironside and Diane Ritchie Structural Studies of PrionsHolger Wille and Jesus Requena Protein Misfolding Cyclic AmplificationFabio ModaBiochemical Characterization of PrionsGianluigi ZanussoTranscriptomics and Genomics of Prion DiseasesGiuseppe Legname and Silvia Vanni Therapeutic Approaches to Prion DiseasesMaria Laura BolognesiBiosafety of PrionsFabio Moda
- ISBN: 978-0-12-811226-7
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 300
- Fecha Publicación: 01/09/2017
- Nº Volúmenes: 1
- Idioma: Inglés