Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Features chapter contributions from leading international scientists and cliniciansProvides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and -omics based approaches INDICE: Part I. Reproductive Tract Development and Gametogenesis 1. Developmental Genetics of the Male Reproductive System 2. Genetics and genomics of early gonad development 3. Genetic Analysis of Meiotic Chromosome Dynamics and Fertility 4. Aging and Sperm Chromatin Quality 5. In Vitro Spermatogenesis from Embryonic Stem Cells 6. Developmental Genetics of the Female Reproductive Tract 7. Molecular Genetics of Oogenesis 8. Epigenetic Control of Oocyte Development 9. RNA Binding Protein Networks and Translational Control in Oocytes 10. Translational Regulation of Gene Expression During Oogenesis and Pre-Implantation Embryo Development 11. MicroRNAs in Gametes and Preimplantation Embryos: Clinical Implications Part II. Embryo Implantation, Placenta Development and Pregnancy 12. Mechanisms of Embryo Implantation and Implantation Failure 13. Transcriptomics of the Human Endometrium and Embryo Implantation 14. Maternal Recognition of Pregnancy 15. Human Genetics at the Fetal-Maternal Interface 16. Epigenetic Modifications in the Human Placenta 17. Micro RNA in the Human Placenta and Pre-eclampsia 18. Genetics and Genomics of Preterm Birth 19. The Intergenerational Effects on Fetal Programming Part III. Infertility and Assisted Reproductive Technology 20. Genetic Testing in Male Infertility 21. Genetics and Genomics of Endometriosis 22. Genetics and Genomics of Primary Ovarian Insufficiency 23. Genetics of Polycystic Ovary Syndrome 24. Genetics and Genomics of Recurrent Pregnancy Loss 25. Human Genetics and Assisted Reproduction 26. Uterine Transplantation Part IV. Preimplantation/Prenatal Genetic Diagnosis and Screening 27. Preimplantation Genetic Diagnosis (PGD) and Screening (PGS) 28. Molecular Genetics in Preimplantation Diagnosis and Screening 29. Epidemiology and Genetics of Human Aneuploidy 30. Next Generation Sequencing for Gene Panels and Clinical Exomes 31. Chromosomal Microarrays and Exome Sequencing for Diagnosis of Fetal Abnormalities 32. Noninvasive Prenatal Testing for Genetic Diseases 33. Non-Invasive Prenatal Testing by Cell-Free DNA: Technology, Biology, Clinical Utility and Limitations 34. Prenatal diagnosis and treatment of genetic steroid disorders 35. Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy
- ISBN: 978-0-12-813570-9
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 552
- Fecha Publicación: 01/11/2018
- Nº Volúmenes: 1
- Idioma: Inglés